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4qgx

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==Crystal sturcture of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution==
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==Crystal structure of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution==
<StructureSection load='4qgx' size='340' side='right'caption='[[4qgx]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
<StructureSection load='4qgx' size='340' side='right'caption='[[4qgx]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4qgx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QGX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4qgx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QGX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LMC:(2E,4E,6E)-3-METHYL-6-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)HEXA-2,4-DIENAL'>LMC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.471&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qgw|4qgw]], [[4qgv|4qgv]], [[3fep|3fep]], [[4exz|4exz]], [[4eej|4eej]], [[3f8a|3f8a]], [[2g7b|2g7b]], [[4i9s|4i9s]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LMC:(2E,4E,6E)-3-METHYL-6-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)HEXA-2,4-DIENAL'>LMC</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRABP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgx OCA], [https://pdbe.org/4qgx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qgx RCSB], [https://www.ebi.ac.uk/pdbsum/4qgx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgx ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgx OCA], [http://pdbe.org/4qgx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qgx RCSB], [http://www.ebi.ac.uk/pdbsum/4qgx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgx ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RABP2_HUMAN RABP2_HUMAN]] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
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[https://www.uniprot.org/uniprot/RABP2_HUMAN RABP2_HUMAN] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Cellular retinoic acid-binding protein|Cellular retinoic acid-binding protein]]
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*[[Cellular retinoic acid-binding protein 3D structures|Cellular retinoic acid-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Geiger, J H]]
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[[Category: Geiger JH]]
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[[Category: Nosrati, M]]
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[[Category: Nosrati M]]
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[[Category: Yapici, I]]
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[[Category: Yapici I]]
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[[Category: Fluorescent protein tag]]
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[[Category: Merocyanine dyes for fluorescent protein labeling]]
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[[Category: Merocyanine protonated schiff base iminium]]
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[[Category: Protein binding]]
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[[Category: Protein engineering]]
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[[Category: Protein fluorescence]]
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Current revision

Crystal structure of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution

PDB ID 4qgx

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