4qwe
From Proteopedia
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<StructureSection load='4qwe' size='340' side='right'caption='[[4qwe]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='4qwe' size='340' side='right'caption='[[4qwe]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4qwe]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4qwe]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QWE FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FTD:[(2R,5S)-5-(4-AMINO-5-FLUORO-2-OXO-3,6-DIHYDROPYRIMIDIN-1(2H)-YL)-1,3-OXATHIOLAN-2-YL]METHYL+TRIHYDROGEN+DIPHOSPHATE'>FTD</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FTD:[(2R,5S)-5-(4-AMINO-5-FLUORO-2-OXO-3,6-DIHYDROPYRIMIDIN-1(2H)-YL)-1,3-OXATHIOLAN-2-YL]METHYL+TRIHYDROGEN+DIPHOSPHATE'>FTD</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qwe OCA], [https://pdbe.org/4qwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qwe RCSB], [https://www.ebi.ac.uk/pdbsum/4qwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qwe ProSAT]</span></td></tr> | |
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- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/DPO4_SACS2 DPO4_SACS2] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis. |
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==See Also== | ==See Also== | ||
- | *[[DNA polymerase|DNA polymerase]] | + | *[[DNA polymerase 3D structures|DNA polymerase 3D structures]] |
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: DNA-directed DNA polymerase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: | + | [[Category: Saccharolobus solfataricus P2]] |
- | [[Category: Gaur | + | [[Category: Gaur V]] |
- | [[Category: Suo | + | [[Category: Suo Z]] |
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Current revision
TERNARY CRYSTAL STRUCTURES of A Y-FAMILY DNA POLYMERASE DPO4 FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH DNA AND (-)FTC-DP
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