Caspase 3D structures

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(New page: ==3D structures of caspase== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *CASP-1 **3e4c – hpro-CASP (mut...)
Current revision (10:36, 14 November 2022) (edit) (undo)
 
(3 intermediate revisions not shown.)
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**[[2h4w]], [[2h4y]], [[2h51]], [[2h54]], [[2hbr]], [[2hby]], [[2hbz]], [[2h48]], [[2fqq]], [[1rwk]], [[1rwm]], [[1rwn]], [[1rwo]], [[1rwp]], [[1rwv]], [[1rww]], [[1rwx]] - hCASP (mutant) + inhibitor<br />
**[[2h4w]], [[2h4y]], [[2h51]], [[2h54]], [[2hbr]], [[2hby]], [[2hbz]], [[2h48]], [[2fqq]], [[1rwk]], [[1rwm]], [[1rwn]], [[1rwo]], [[1rwp]], [[1rwv]], [[1rww]], [[1rwx]] - hCASP (mutant) + inhibitor<br />
**[[1ice]] – hCASP + tetrapeptide aldehyde<br />
**[[1ice]] – hCASP + tetrapeptide aldehyde<br />
 +
**[[6vie]] – hCASP + gasdermin<br />
 +
**[[6kn0]] – hCASP (mutant) + gasdermin<br />
 +
**[[6pzp]] – hCASP + VX-765<br />
 +
**[[7keu]] – hCASP CARD domain + ASC CARD domain – Cryo-EM<br />
**[[1m72]] – SfCASP + polypeptide inhibitor<br />
**[[1m72]] – SfCASP + polypeptide inhibitor<br />
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**[[2xzd]], [[2xzt]], [[2y0b]] - hCASP subunits P12, P17 + DARPIN-3.4<br />
**[[2xzd]], [[2xzt]], [[2y0b]] - hCASP subunits P12, P17 + DARPIN-3.4<br />
**[[3pcx]], [[3pd1]], [[3pd0]], [[3gjq]], [[3gjr]], [[3gjs]], [[3gjt]], [[3edq]], [[3edr]], [[2cnk]], [[2cnl]], [[2cnn]], [[2cno]], [[2cdr]], [[2h65]], [[1cp3]], [[1pau]], [[4pry]] – hCASP + polypeptide inhibitor<br />
**[[3pcx]], [[3pd1]], [[3pd0]], [[3gjq]], [[3gjr]], [[3gjs]], [[3gjt]], [[3edq]], [[3edr]], [[2cnk]], [[2cnl]], [[2cnn]], [[2cno]], [[2cdr]], [[2h65]], [[1cp3]], [[1pau]], [[4pry]] – hCASP + polypeptide inhibitor<br />
-
**[[4dcj]], [[4dco]], [[4dcp]], [[4eha]], [[4ehd]], [[4ehf]], [[4ehh]], [[4ehk]], [[4ehl]], [[4ehn]], [[4ps0]], [[4ps1]] – hCASP subunits P12, P17 + polypeptide inhibitor<br />
+
**[[4dcj]], [[4dco]], [[4dcp]], [[4eha]], [[4ehd]], [[4ehf]], [[4ehh]], [[4ehk]], [[4ehl]], [[4ehn]], [[4ps0]], [[4ps1]], [[6ckz]], [[7rn7]], [[7rn8]], [[7rn9]], [[7rna]], [[7rnb]], [[7rnc]], [[7rnd]], [[7rne]], [[7rnf]], [[7rng]], [[7seo]], [[7uso]], [[7usp]], [[7usq]] – hCASP subunits P12, P17 + polypeptide inhibitor<br />
**[[2dko]], [[2cjx]], [[2cjy]], [[4qtx]], [[4qty]], [[4qu0]], [[4qu5]], [[4qu8]], [[4qu9]], [[4qua]], [[4qub]] [[4qud]], [[4que]], [[4qug]], [[4quh]], [[4qui]], [[4quj]], [[4qul]], [[5i9b]], [[5i9t]], [[5iab]], [[5iae]], [[5iag]], [[5iaj]], [[5iak]], [[5ian]], [[5iar]], [[5ias]], [[5ibc]], [[5ibp]], [[5ibr]], [[4qud]], [[6bfj]], [[6bfk]], [[6bfl]], [[6bfo]], [[6bg0]], [[6bg1]], [[6bg4]], [[6bgk]], [[6bgq]], [[6bgr]], [[6bgs]], [[6bh9]], [[6bha]], [[6bdv]] - hCASP (mutant) + polypeptide inhibitor<br />
**[[2dko]], [[2cjx]], [[2cjy]], [[4qtx]], [[4qty]], [[4qu0]], [[4qu5]], [[4qu8]], [[4qu9]], [[4qua]], [[4qub]] [[4qud]], [[4que]], [[4qug]], [[4quh]], [[4qui]], [[4quj]], [[4qul]], [[5i9b]], [[5i9t]], [[5iab]], [[5iae]], [[5iag]], [[5iaj]], [[5iak]], [[5ian]], [[5iar]], [[5ias]], [[5ibc]], [[5ibp]], [[5ibr]], [[4qud]], [[6bfj]], [[6bfk]], [[6bfl]], [[6bfo]], [[6bg0]], [[6bg1]], [[6bg4]], [[6bgk]], [[6bgq]], [[6bgr]], [[6bgs]], [[6bh9]], [[6bha]], [[6bdv]] - hCASP (mutant) + polypeptide inhibitor<br />
**[[3kjf]], [[3h0e]], [[3deh]], [[3dei]], [[3dej]], [[3dek]], [[1re1]], [[1rhj]], [[1rhk]], [[1rhm]], [[1rhq]], [[1rhr]], [[1rhu]], [[1nme]], [[1nmq]], [[1nms]], [[1gfw]] – hCASP + inhibitor<br />
**[[3kjf]], [[3h0e]], [[3deh]], [[3dei]], [[3dej]], [[3dek]], [[1re1]], [[1rhj]], [[1rhk]], [[1rhm]], [[1rhq]], [[1rhr]], [[1rhu]], [[1nme]], [[1nmq]], [[1nms]], [[1gfw]] – hCASP + inhibitor<br />
**[[3itn]], [[2j30]], [[2j31]], [[2j32]], [[2j33]], [[2c1e]], [[2c2k]], [[2c2m]], [[2c2o]], [[2c2z]], [[2h5i]], [[2h5j]], [[4jr0]] – hpro-CASP + polypeptide inhibitor<br />
**[[3itn]], [[2j30]], [[2j31]], [[2j32]], [[2j33]], [[2c1e]], [[2c2k]], [[2c2m]], [[2c2o]], [[2c2z]], [[2h5i]], [[2h5j]], [[4jr0]] – hpro-CASP + polypeptide inhibitor<br />
-
[[4jqy]], [[4jqz]] - hpro-CASP (mutant)<br />
+
**[[4jqy]], [[4jqz]] - hpro-CASP (mutant)<br />
-
**[[1i3o]] - hCASP (mutant) + XIAP-BIR2
+
**[[1i3o]] - hCASP (mutant) + XIAP-BIR2<br />
 +
**[[6wi4]] – CASP + inhibitor – ''Porites asteroides''<br />
 +
 
 +
*CASP-4
 +
 
 +
**[[6nry]] – hCASP <br />
 +
**[[6kmz]] – hCASP (mutant) + gasdermin<br />
 +
**[[6kmt]], [[6kmu]], [[6kn1]] – mCASP (mutant) - mouse<br />
 +
**[[6kmv]] – mCASP (mutant) + gasdermin<br />
*CASP-6
*CASP-6
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**[[4hva]] - hCASP subunit P11 + P18 + VEID inhibitor<br />
**[[4hva]] - hCASP subunit P11 + P18 + VEID inhibitor<br />
**[[4n5d]] - hCASP subunit P11 + P18 + inhibitor<br />
**[[4n5d]] - hCASP subunit P11 + P18 + inhibitor<br />
 +
**[[6ppm]] - hCASP subunit P11 + P18 + polypeptide inhibitor<br />
**[[4n6g]], [[4n7j]], [[4n7m]], [[4nbk]], [[4nbl]], [[4nbn]] - hCASP subunit P11 + P18 (mutant) + inhibitor<br />
**[[4n6g]], [[4n7j]], [[4n7m]], [[4nbk]], [[4nbl]], [[4nbn]] - hCASP subunit P11 + P18 (mutant) + inhibitor<br />
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**[[3ibc]], [[2ql5]], [[2ql7]], [[2ql9]], [[2qlb]], [[2qlf]], [[2qlj]], [[3edr]] - hCASP large subunit + polypeptide inhibitor<br />
**[[3ibc]], [[2ql5]], [[2ql7]], [[2ql9]], [[2qlb]], [[2qlf]], [[2qlj]], [[3edr]] - hCASP large subunit + polypeptide inhibitor<br />
**[[1f1j]], [[4hqr]] - hCASP + polypeptide inhibitor<br />
**[[1f1j]], [[4hqr]] - hCASP + polypeptide inhibitor<br />
 +
**[[7wzs]] – hCASP + calmodulin + CopC <br />
**[[3h1p]], [[4jr1]], [[4jr2]] - hCASP catalytic domain (mutant) + polypeptide inhibitor<br />
**[[3h1p]], [[4jr1]], [[4jr2]] - hCASP catalytic domain (mutant) + polypeptide inhibitor<br />
**[[1shj]], [[1shl]] - hCASP catalytic domain (mutant) + inhibitor<br />
**[[1shj]], [[1shl]] - hCASP catalytic domain (mutant) + inhibitor<br />
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**[[1i4o]] - hCASP P20 subunit + XIAP<br />
**[[1i4o]] - hCASP P20 subunit + XIAP<br />
**[[4jb8]], [[4lsz]] - hCASP large+small subunits + DARPIN<br />
**[[4jb8]], [[4lsz]] - hCASP large+small subunits + DARPIN<br />
-
**[[5ic6]], [[5ic4]], [[4zvo]], [[4zvp]], [[4zvq]], [[4zvr]], [[4zvs]], [[4zvt]], [[4zvu]], [[6cl2]], [[6cl1]], [[6cl0]], [[6ckz]] - hCASP large+small subunits + peptide inhibitor<br />
+
**[[5ic6]], [[5ic4]], [[4zvo]], [[4zvp]], [[4zvq]], [[4zvr]], [[4zvs]], [[4zvt]], [[4zvu]], [[6cl2]], [[6cl1]], [[6cl0]] - hCASP large+small subunits + peptide inhibitor<br />
*CASP-8
*CASP-8
**[[5l08]] – hCASP – Cryo-EM<br />
**[[5l08]] – hCASP – Cryo-EM<br />
-
**[[4zbw]] - hCASP death effector domain<br />
+
**[[6xkj]] – hCASP CARD domain 451-537 – Cryo-EM<br />
 +
**[[4zbw]], [[7lvj]], [[7lvm]] - hCASP death effector domain<br />
**[[5h33]], [[5h31]] - hCASP death effector domain (mutant)<br />
**[[5h33]], [[5h31]] - hCASP death effector domain (mutant)<br />
 +
**[[6agw]] - hCASP pro domain 1-180<br />
**[[3kjn]], [[3kjq]] – hCASP subunit P18 + inhibitor<br />
**[[3kjn]], [[3kjq]] – hCASP subunit P18 + inhibitor<br />
**[[1f9e]], [[1qtn]], [[1qdu]] - hCASP subunit α,β + polypeptide inhibitor<br />
**[[1f9e]], [[1qtn]], [[1qdu]] - hCASP subunit α,β + polypeptide inhibitor<br />
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**[[3h11]] - hCASP (mutant) + polypeptide inhibitor<br />
**[[3h11]] - hCASP (mutant) + polypeptide inhibitor<br />
**[[2y1l]] - hCASP subunits P18 P10<br />
**[[2y1l]] - hCASP subunits P18 P10<br />
-
**[[2k7z]] – hpro-CASP (mutant) – NMR<br />
+
**[[6px9]] - hpro-CASP catalytic domain 276-538 + inhibitor<br />
 +
**[[2k7z]] – hpro-CASP catalytic domain (mutant) – NMR<br />
**[[2fun]], [[1i4e]] – CASP + P35 – ''Autographa californica''
**[[2fun]], [[1i4e]] – CASP + P35 – ''Autographa californica''
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**[[1nw9]] – hCASP catalytic domain + XIAP-BIR3<br />
**[[1nw9]] – hCASP catalytic domain + XIAP-BIR3<br />
**[[3ygs]], [[4rhw]] – hpro-CASP + APAF-1 CARD
**[[3ygs]], [[4rhw]] – hpro-CASP + APAF-1 CARD
 +
 +
*CASP-11
 +
 +
**[[6ns7]] – mCASP 60-243<br />
 +
**[[6kxg]] – mCASP CARD domain 1-463<br />
*''Drosophila melanogaster'' CASP
*''Drosophila melanogaster'' CASP

Current revision

3D structures of caspase

Updated on 14-November-2022

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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