Catechol O-methyltransferase
From Proteopedia
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| - | == 3D Structures of catechol O-methyltransferase == | ||
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| - | *Catechol O-methyltransferase | ||
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| - | **[[4pyi]], [[4pyj]], [[4pyk]] – hCOMT – human <BR /> | ||
| - | **[[2zlb]], [[4p7g]], [[4p7j]] – rCOMT – rat <BR /> | ||
| - | **[[4pym]] – rCOMT (mutant) <BR /> | ||
| - | **[[4p7f]] – mCOMT - mouse<BR /> | ||
| - | **[[6aw4]] – NgCOMT – ''Nannospalax galili''<BR /> | ||
| - | **[[6aw5]], [[6aw6]] – NgCOMT (mutant) <BR /> | ||
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| - | *Catechol O-methyltransferase binary complexes | ||
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| - | **[[2avd]] – hCOMT + SAM <BR /> | ||
| - | **[[2zth]] – rCOMT + SAM <BR /> | ||
| - | **[[3u81]], [[4pyn]], [[4pyo]] – rCOMT (mutant) + SAH<BR /> | ||
| - | **[[4pyq]] – rCOMT (mutant) + ureido-benzamidine<BR /> | ||
| - | **[[1jr4]], [[3hvh]], [[3hvi]], [[3hvj]], [[3hvk]], [[3a7d]], [[3nw9]], [[3nwb]], [[3nwe]], [[5k01]], [[5k03]], [[5k05]], [[5k09]], [[5k0b]], [[5k0c]], [[5k0e]], [[5k0f]], [[5k0g]], [[5k0j]], [[5k0l]], [[5k0n]], [[5lqa]], [[5lqc]], [[5lqj]], [[5lqk]], [[5lqn]], [[5lqr]], [[5lqu]], [[5lr6]], [[6gy1]] – rCOMT + inhibitor<BR /> | ||
| - | **[[3oe4]], [[3oe5]], [[3ozr]], [[3ozs]], [[3ozt]], [[3r6t]], [[5p8w]], [[5p8x]], [[5p8y]], [[5p8z]], [[5p90]], [[5p91]], [[5p92]], [[5p93]], [[5p94]], [[5p95]], [[5p96]], [[5p97]], [[5p98]], [[5p99]], [[5p9a]], [[5p9b]], [[5p9c]], [[5p9d]], [[5p9e]], [[5p93]], [[5p9n]], [[5p9o]], [[5p9p]], [[5p9q]], [[5p9r]], [[5p9s]], [[5p9t]], [[5p9u]], [[5p9v]], [[5p9w]], [[5p9x]], [[5p9y]], [[5p9z]], [[5pa0]], [[5pa1]], [[5pa2]], [[5pa3]], [[5pa4]], [[5pa5]], [[5pa6]], [[5pa7]] – rCOMT (mutant) + inhibitor<BR /> | ||
| - | **[[4p7k]], [[4pyl]] – rCOMT + sinefungin<BR /> | ||
| - | **[[4p58]] – mCOMT + inhibitor <BR /> | ||
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| - | *Catechol O-methyltransferase ternary complexes | ||
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| - | **[[3bwy]], [[4xuc]] – hCOMT (mutant) + SAM + dinitrocatechol <BR /> | ||
| - | **[[4xue]] – hCOMT + SAM + catechol mimic<BR /> | ||
| - | **[[4xuc]], [[4xud]] – hCOMT (mutant) + SAM + catechol mimic<BR /> | ||
| - | **[[5fhq]], [[1vid]] – rCOMT + SAM + dinitrocatechol <BR /> | ||
| - | **[[5fhr]] – rCOMT (mutant) + SAM + dinitrocatechol <BR /> | ||
| - | **[[1h1d]], [[2cl5]], [[2zvj]], [[3s68]] – rCOMT + inhibitor + SAM<BR /> | ||
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| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
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References
- ↑ Tsuji E, Okazaki K, Isaji M, Takeda K. Crystal structures of the Apo and Holo form of rat catechol-O-methyltransferase. J Struct Biol. 2008 Dec 10. PMID:19111934 doi:S1047-8477(08)00293-1
- ↑ Muller T. Catechol-O-methyltransferase inhibitors in Parkinson's disease. Drugs. 2015 Feb;75(2):157-74. doi: 10.1007/s40265-014-0343-0. PMID:25559423 doi:http://dx.doi.org/10.1007/s40265-014-0343-0
