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6jwm
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6jwm is ON HOLD Authors: Li, K., Kuang, Z. Description: Crystal structure of the SPRY domain of SPSB2 in complex with cR7, a potent cyclic peptide ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the SPRY domain of SPSB2 in complex with cR7, a potent cyclic peptide inhibitor of SPSB2-iNOS interaction== | |
| - | + | <StructureSection load='6jwm' size='340' side='right'caption='[[6jwm]], [[Resolution|resolution]] 1.23Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6jwm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JWM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JWM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.23Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jwm OCA], [https://pdbe.org/6jwm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jwm RCSB], [https://www.ebi.ac.uk/pdbsum/6jwm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jwm ProSAT]</span></td></tr> |
| - | [[Category: Kuang | + | </table> |
| - | [[Category: Li | + | == Function == |
| + | [https://www.uniprot.org/uniprot/SPSB2_HUMAN SPSB2_HUMAN] Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.<ref>PMID:15601820</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Kuang Z]] | ||
| + | [[Category: Li K]] | ||
Current revision
Crystal structure of the SPRY domain of SPSB2 in complex with cR7, a potent cyclic peptide inhibitor of SPSB2-iNOS interaction
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