6jwn

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(New page: '''Unreleased structure''' The entry 6jwn is ON HOLD Authors: Li, K., Kuang, Z. Description: Crystal structure of the SPRY domain of SPSB2 in complex with cR9, a cyclic peptide inhibit...)
Current revision (10:40, 27 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 6jwn is ON HOLD
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==Crystal structure of the SPRY domain of SPSB2 in complex with cR9, a cyclic peptide inhibitor of SPSB-iNOS interaction==
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<StructureSection load='6jwn' size='340' side='right'caption='[[6jwn]], [[Resolution|resolution]] 1.61&Aring;' scene=''>
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Authors: Li, K., Kuang, Z.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6jwn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JWN FirstGlance]. <br>
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Description: Crystal structure of the SPRY domain of SPSB2 in complex with cR9, a cyclic peptide inhibitor of SPSB-iNOS interaction
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.61&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jwn OCA], [https://pdbe.org/6jwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jwn RCSB], [https://www.ebi.ac.uk/pdbsum/6jwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jwn ProSAT]</span></td></tr>
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[[Category: Kuang, Z]]
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</table>
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[[Category: Li, K]]
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== Function ==
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[https://www.uniprot.org/uniprot/SPSB2_HUMAN SPSB2_HUMAN] Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.<ref>PMID:15601820</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Kuang Z]]
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[[Category: Li K]]

Current revision

Crystal structure of the SPRY domain of SPSB2 in complex with cR9, a cyclic peptide inhibitor of SPSB-iNOS interaction

PDB ID 6jwn

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