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6rj0
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6rj0 is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Atlantic Cod Nervous Necrosis Virus-Like Particle produced in Nicotiana benthamiana== | |
| + | <SX load='6rj0' size='340' side='right' viewer='molstar' caption='[[6rj0]], [[Resolution|resolution]] 3.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6rj0]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Betanodavirus_sp. Betanodavirus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RJ0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rj0 OCA], [https://pdbe.org/6rj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rj0 RCSB], [https://www.ebi.ac.uk/pdbsum/6rj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rj0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CAPSD_SJNNV CAPSD_SJNNV] Capsid protein alpha self-assembles to form an icosahedral procapsid with a T=3 symmetry, about 30 nm in diameter, and consisting of 60 capsid proteins trimers. The capsid encapsulates the two genomic RNAs (By similarity). | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Virus-like particles (VLPs) of the fish virus, Atlantic Cod Nervous necrosis virus (ACNNV), were successfully produced by transient expression of the coat protein in Nicotiana benthamiana plants. VLPs could also be produced in transgenic tobacco BY-2 cells. The protein extracted from plants self-assembled into T = 3 particles, that appeared to be morphologically similar to previously analyzed NNV VLPs when analyzed by high resolution cryo-electron microscopy. Administration of the plant-produced VLPs to sea bass (Dicentrarchus labrax) showed that they could protect the fish against subsequent virus challenge, indicating that plant-produced vaccines may have a substantial future role in aquaculture. | ||
| - | + | Plant-Made Nervous Necrosis Virus-Like Particles Protect Fish Against Disease.,Marsian J, Hurdiss DL, Ranson NA, Ritala A, Paley R, Cano I, Lomonossoff GP Front Plant Sci. 2019 Jul 9;10:880. doi: 10.3389/fpls.2019.00880. eCollection, 2019. PMID:31354759<ref>PMID:31354759</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 6rj0" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Betanodavirus sp]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hurdiss DL]] | ||
| + | [[Category: Ranson NA]] | ||
Current revision
Atlantic Cod Nervous Necrosis Virus-Like Particle produced in Nicotiana benthamiana
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