4rwh

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<StructureSection load='4rwh' size='340' side='right'caption='[[4rwh]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4rwh' size='340' side='right'caption='[[4rwh]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4rwh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RWH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4rwh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RWH FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd80, B7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.802&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rwh OCA], [http://pdbe.org/4rwh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rwh RCSB], [http://www.ebi.ac.uk/pdbsum/4rwh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rwh ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rwh OCA], [https://pdbe.org/4rwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rwh RCSB], [https://www.ebi.ac.uk/pdbsum/4rwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rwh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CD80_MOUSE CD80_MOUSE]] Involved in the costimulatory signal essential for T lymphocytes activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
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[https://www.uniprot.org/uniprot/CD80_MOUSE CD80_MOUSE] Involved in the costimulatory signal essential for T lymphocytes activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Almo, S C]]
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[[Category: Almo SC]]
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[[Category: Fedorov, A A]]
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[[Category: Fedorov AA]]
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[[Category: Fedorov, E V]]
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[[Category: Fedorov EV]]
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[[Category: Hillerich, B]]
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[[Category: Hillerich B]]
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[[Category: Samanta, D]]
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[[Category: Samanta D]]
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[[Category: Seidel, R D]]
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[[Category: Seidel RD]]
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[[Category: Ig fold]]
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[[Category: Signaling protein]]
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[[Category: T cell costimulatory ligand b7-1]]
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Current revision

Crystal structure of T cell costimulatory ligand B7-1 (CD80)

PDB ID 4rwh

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