Centromere protein 3D structure
From Proteopedia
(Difference between revisions)
(New page: ==3D structures of centromere protein== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Centromere proteins X, S, ...) |
|||
(3 intermediate revisions not shown.) | |||
Line 6: | Line 6: | ||
*Centromere proteins X, S, W, T | *Centromere proteins X, S, W, T | ||
- | **[[3b0b]] – cCENP-X + CENP-S – chicken<br /> | ||
**[[4dra]], [[4e44]], [[4ne3]], [[4ne5]], [[4ne6]] – hCENP-X + CENP-S – human<br /> | **[[4dra]], [[4e44]], [[4ne3]], [[4ne5]], [[4ne6]] – hCENP-X + CENP-S – human<br /> | ||
- | **[[3vh5]], [[3vh6]] – cCENP-X + CENP-S (mutant) + CENP-W + CENP-T C-terminal (mutant)<br /> | ||
**[[4drb]], [[4e45]] – hCENP-X + CENP-S + Fanconi anemia group M protein<br /> | **[[4drb]], [[4e45]] – hCENP-X + CENP-S + Fanconi anemia group M protein<br /> | ||
**[[4ndy]], [[4ne1]] – hCENP-X + CENP-S + DNA<br /> | **[[4ndy]], [[4ne1]] – hCENP-X + CENP-S + DNA<br /> | ||
+ | **[[3b0b]], [[7da0]], [[7da1]] – cCENP-X + CENP-S – chicken<br /> | ||
+ | **[[7da2]] – cCENP-X + CENP-S + Fanconi anemia group M protein<br /> | ||
**[[3b0c]], [[3b0d]] – cCENP-T + CENP-W<br /> | **[[3b0c]], [[3b0d]] – cCENP-T + CENP-W<br /> | ||
**[[3vza]] – cCENP-T residues 63-98 (mutant) + Spc24 + Spc25<br /> | **[[3vza]] – cCENP-T residues 63-98 (mutant) + Spc24 + Spc25<br /> | ||
+ | **[[3vh5]], [[3vh6]] – cCENP-X + CENP-S (mutant) + CENP-W + CENP-T C-terminal (mutant)<br /> | ||
*Inner centromere protein | *Inner centromere protein | ||
+ | **[[4af3]], [[6gr8]], [[6gr9]] – hINCENP residues 835-903 + aurora kinase + inhibitor<br /> | ||
+ | **[[2qfa]], [[6yie]] – hINCENP residues 1-47 + survivin + borealin<br /> | ||
+ | **[[6yif]], [[6yih]] – hINCENP residues 7-57 + survivin + borealin + histone H3<br /> | ||
**[[2bfx]], [[4b8l]] – fINCENP residues 798-840 + aurora kinase – frog<br /> | **[[2bfx]], [[4b8l]] – fINCENP residues 798-840 + aurora kinase – frog<br /> | ||
**[[2bfy]] – fINCENP residues 798-840 + aurora kinase + hesperadin<br /> | **[[2bfy]] – fINCENP residues 798-840 + aurora kinase + hesperadin<br /> | ||
**[[2vgp]], [[2vrx]], [[3ztx]], [[4b8m]], [[5k3y]], [[5eyk]] – fINCENP residues 798-840 + aurora kinase + inhibitor<br /> | **[[2vgp]], [[2vrx]], [[3ztx]], [[4b8m]], [[5k3y]], [[5eyk]] – fINCENP residues 798-840 + aurora kinase + inhibitor<br /> | ||
- | **[[4af3]] – hINCENP residues 835-903 + aurora kinase + inhibitor<br /> | ||
**[[2vgo]] – fINCENP residues 798-840 + aurora kinase + reversine<br /> | **[[2vgo]] – fINCENP residues 798-840 + aurora kinase + reversine<br /> | ||
**[[4c2v]] – fINCENP residues 798-840 + aurora kinase + barasertib<br /> | **[[4c2v]] – fINCENP residues 798-840 + aurora kinase + barasertib<br /> | ||
**[[4c2w]] – fINCENP residues 798-840 + aurora kinase + AMPPNP<br /> | **[[4c2w]] – fINCENP residues 798-840 + aurora kinase + AMPPNP<br /> | ||
- | **[[ | + | **[[6o2d]] – fyNCENP subunit CNP3 – fission yeast<br /> |
+ | **[[6oua]] – yNCENP subunits CTF3 complex – yeast – Cryo EM<br /> | ||
+ | **[[6nuw]] – yNCENP CTF19 complex – Cryo EM<br /> | ||
+ | **[[6oua]] – yNCENP subunits CTF3+MCM16+MCM22+WIP1+CNN1 – Cryo EM<br /> | ||
+ | **[[6qle]] – yNCENP CCAN complex – Cryo EM<br /> | ||
+ | **[[6qld]] – yNCENP CCAN-CENP-A complex – Cryo EM<br /> | ||
+ | **[[6qlf]] – yNCENP CCAN complex + MASK1 – Cryo EM<br /> | ||
*Centromere protein A | *Centromere protein A | ||
Line 31: | Line 40: | ||
**[[3r45]] – hCENP-A + histone H4 + Holliday junction recognition protein<br /> | **[[3r45]] – hCENP-A + histone H4 + Holliday junction recognition protein<br /> | ||
**[[3an2]] – hCENP-A + histone H4 + histone H2A + histone H2B + DNA<br /> | **[[3an2]] – hCENP-A + histone H4 + histone H2A + histone H2B + DNA<br /> | ||
- | **[[6buz]] – hCENP-A + histone H4 + histone H2A + histone H2B + DNA + MBP/CENP-N<br /> | + | **[[6l49]], [[6o1d]], [[6se0]], [[6seg]], [[6tem]] – hCENP-A + histone H4 + histone H2A + histone H2B + DNA – Cryo EM<br /> |
+ | **[[6buz]] – hCENP-A + histone H4 + histone H2A + histone H2B + DNA + MBP/CENP-N - Cryo EM<br /> | ||
+ | **[[6eoc]], [[6e0p]] – hCENP-A + histone H4 + histone H2A + histone H2B + DNA + scFv – Cryo EM<br /> | ||
+ | **[[7d20]] – hCENP-A + histone H4 + histone H2A + histone H2B + DNA + Set-8 – Cryo EM<br /> | ||
+ | **[[7bxt]] – cCENP-A + histone H4 + histone H2A + histone H2B + DNA – Cryo EM<br /> | ||
+ | **[[7pkn]], [[7pii]], [[7qoo]], [[7r5r]], [[7r5s]], [[7r5v]], [[7u46]], [[7u47]], [[7u4d]], [[7ywx]], [[7yyh]] – hCENP in nucleosome – Cryo EM<br /> | ||
*Centromere protein C | *Centromere protein C | ||
- | **[[5lsk]], [[5lsj]] – hCENP-C + kinetochore | + | **[[5lsk]], [[5lsj]] – hCENP-C + kinetochore mis12<br /> |
+ | **[[6se6]], [[6see]], [[6sef]] – hCENP-C + histones + DNA - Cryo EM<br /> | ||
+ | **[[6o2k]], [[6xwu]] – CENP-C cupin domain – ''Drosophila melanogaster''<br /> | ||
*Centromere protein B | *Centromere protein B | ||
Line 45: | Line 61: | ||
*Centromere protein E | *Centromere protein E | ||
- | **[[1t5c]] – hCENP-E motor domain<br /> | + | **[[1t5c]], [[6m4i]] – hCENP-E motor domain 1-339<br /> |
+ | **[[8hfh]] – hCENP-E motor domain + AMPPNP<br /> | ||
+ | **[[8owi]] – hCENP-E corona-targeting domain 2452-2598<br /> | ||
+ | **[[8whl]] – hCENP-E 487-548 + CLASP2<br /> | ||
*Centromere protein I | *Centromere protein I | ||
Line 54: | Line 73: | ||
**[[5itz]] – hCENP-J + tubulin<br /> | **[[5itz]] – hCENP-J + tubulin<br /> | ||
+ | **[[7q1e]], [[7q1f]] – hCENP-J + tubulin + IE5<br /> | ||
+ | **[[7z0f]], [[7z0g]] – hCENP-J 320-397 + tubulin + IIH5<br /> | ||
*Centromere protein M | *Centromere protein M | ||
Line 62: | Line 83: | ||
**[[4wau]], [[6eqt]] – hCENP-N<br /> | **[[4wau]], [[6eqt]] – hCENP-N<br /> | ||
- | **[[6c0w]] – hCENP-N + histone H4 + histone H2A + histone H2B + DNA + CENP-A<br /> | + | **[[6c0w]] – hCENP-N + histone H4 + histone H2A + histone H2B + DNA + CENP-A - Cryo EM<br /> |
+ | **[[6muo]], [[6mup]] – hCENP-N + histone H4 + histone H2A + histone H2B + DNA + CENP-C – Cryo EM<br /> | ||
+ | |||
+ | *Centromere protein 3 (CBF3) or centromere DNA-binding protein complex CBF3 | ||
+ | |||
+ | **[[4aco]] – yCBF3 subunit A <br /> | ||
+ | **[[2quq]], [[2veq]] – yCBF3 subunit B <br /> | ||
+ | **[[6f07]] – yCBF3 subunit B + suppressor of kinetochore protein – Cryo EM <br /> | ||
+ | **[[6fe8]], [[7k79]] – yCBF3 subunits B,C+ suppressor of kinetochore protein – Cryo EM <br /> | ||
+ | **[[6gyp]], [[6gyu]] – yCBF3 subunits A,B,C + suppressor of kinetochore protein – Cryo EM <br /> | ||
+ | **[[6gys]] – yCBF3 subunits A,B,C + suppressor of kinetochore protein + DNA – Cryo EM <br /> | ||
+ | **[[1nex]] – yCBF3 subunit D + peptide <br /> | ||
+ | |||
+ | *Centromere protein A+C | ||
+ | |||
+ | **[[7by0]] – cCENP-A + CENP-C + histone H4 + histone H2A + histone H2B + DNA – Cryo EM <br /> | ||
*Centromere protein I+K+H | *Centromere protein I+K+H | ||
- | **[[5z08]] – CtCENP-I + CENP-K + CENP-H <br /> | + | **[[5z08]], [[7pb4]] – CtCENP-I + CENP-K + CENP-H <br /> |
+ | |||
+ | *Centromere protein O+P+Q+R+U | ||
+ | |||
+ | **[[7pb8]] – hCENP-O + CENP-P + CENP-Q + CENP-R + CENP-U <br /> | ||
+ | |||
+ | *Centromere proteins C+H+I+K+L+M+N+O+P+Q+S+T+U+W+X or kinetochore | ||
+ | |||
+ | **[[7xho]] – hKinetochore – Cryo EM<br /> | ||
+ | **[[7xhn]] – hKinetochore + DNA – Cryo EM<br /> | ||
+ | **[[8ow1]] – yKinetochore + CENP-A – Cryo EM<br /> | ||
*Centromere protein mis12 | *Centromere protein mis12 | ||
- | **[[5wwl]] – fyCENP + kinetochore protein NNF1 | + | **[[5wwl]] – fyCENP + kinetochore protein NNF1<br /> |
*Centromere protein mis16 | *Centromere protein mis16 | ||
**[[5wjc]] – fyCENP + EIC1<br /> | **[[5wjc]] – fyCENP + EIC1<br /> | ||
+ | **[[6s29]] – fyCENP + mis19<br /> | ||
}} | }} |
Current revision
3D structures of centromere protein
Updated on 22-January-2025