6dl7

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<StructureSection load='6dl7' size='340' side='right'caption='[[6dl7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='6dl7' size='340' side='right'caption='[[6dl7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6dl7]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DL7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DL7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6dl7]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DL7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DL7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ONC:7-benzyl-4-[(2-methylphenyl)methyl]-6,7,8,9-tetrahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one'>ONC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_Clp Endopeptidase Clp], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.92 3.4.21.92] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ONC:7-benzyl-4-[(2-methylphenyl)methyl]-6,7,8,9-tetrahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one'>ONC</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dl7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dl7 OCA], [http://pdbe.org/6dl7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dl7 RCSB], [http://www.ebi.ac.uk/pdbsum/6dl7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dl7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dl7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dl7 OCA], [https://pdbe.org/6dl7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dl7 RCSB], [https://www.ebi.ac.uk/pdbsum/6dl7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dl7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CLPP_HUMAN CLPP_HUMAN]] Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates.
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[https://www.uniprot.org/uniprot/CLPP_HUMAN CLPP_HUMAN] Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates.
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==See Also==
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*[[Clp protease 3D structures|Clp protease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Endopeptidase Clp]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Halgas, O]]
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[[Category: Halgas O]]
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[[Category: Pai, E F]]
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[[Category: Pai EF]]
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[[Category: Schimmer, A]]
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[[Category: Schimmer A]]
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[[Category: Zarabi, S F]]
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[[Category: Zarabi SF]]
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[[Category: Degradation]]
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[[Category: Homeostasis]]
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[[Category: Hydrolase]]
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[[Category: Mitochondria]]
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[[Category: Protease]]
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Current revision

Human mitochondrial ClpP in complex with ONC201 (TIC10)

PDB ID 6dl7

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