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1qn2

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cytochrome cH from Methylobacterium extorquens

Structural highlights

1qn2 is a 3 chain structure with sequence from Methylorubrum extorquens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.01Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q7SIA4_METEX

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

Cytochrome cH is the electron donor to the oxidase in methylotrophic bacteria. Its amino acid sequence suggests that it is a typical Class 1 cytochrome c, but some features of the sequence indicated that its structure might be of special interest. The structure of oxidized cytochrome cH has been solved to 2.0 A resolution by X-ray diffraction. It has the classical tertiary structure of the Class 1 cytochromes c but bears a closer gross resemblance to mitochondrial cytochrome c than to the bacterial cytochrome c2. The left-hand side of the haem cleft is unique; in particular, it is highly hydrophobic, the usual water is absent, and the "conserved" Tyr67 is replaced by tryptophan. A number of features of the structure demonstrate that the usual hydrogen bonding network involving water in the haem channel is not essential and that other mechanisms may exist for modulation of redox potentials in this cytochrome.

The molecular structure of an unusual cytochrome c2 determined at 2.0 A; the cytochrome cH from Methylobacterium extorquens.,Read J, Gill R, Dales SL, Cooper JB, Wood SP, Anthony C Protein Sci. 1999 Jun;8(6):1232-40. PMID:10386873^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Read J, Gill R, Dales SL, Cooper JB, Wood SP, Anthony C. The molecular structure of an unusual cytochrome c2 determined at 2.0 A; the cytochrome cH from Methylobacterium extorquens. Protein Sci. 1999 Jun;8(6):1232-40. PMID:10386873

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 See Also
6 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qn2"

@@ Line 3: / Line 3: @@
 <StructureSection load='1qn2' size='340' side='right'caption='[[1qn2]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1qn2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Methylobacterium_extorquens Methylobacterium extorquens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QN2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QN2 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1qn2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylorubrum_extorquens Methylorubrum extorquens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QN2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QN2 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qn2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qn2 OCA], [http://pdbe.org/1qn2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qn2 RCSB], [http://www.ebi.ac.uk/pdbsum/1qn2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qn2 ProSAT]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qn2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qn2 OCA], [https://pdbe.org/1qn2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qn2 RCSB], [https://www.ebi.ac.uk/pdbsum/1qn2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qn2 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q7SIA4_METEX Q7SIA4_METEX]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 28: / Line 31: @@
 ==See Also==
-*[[Cytochrome c|Cytochrome c]]
+*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
 == References ==
 <references/>
@@ Line 34: / Line 37: @@
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Methylobacterium extorquens]]
+[[Category: Methylorubrum extorquens]]
-[[Category: Anthony, C]]
+[[Category: Anthony C]]
-[[Category: Cooper, J B]]
+[[Category: Cooper JB]]
-[[Category: Dales, S L]]
+[[Category: Dales SL]]
-[[Category: Gill, R]]
+[[Category: Gill R]]
-[[Category: Read, J]]
+[[Category: Read J]]
-[[Category: Wood, S P]]
+[[Category: Wood SP]]
-[[Category: Cytochrome]]
-[[Category: Cytochrome c]]
-[[Category: Electron transport]]

1qn2

From Proteopedia

Current revision

cytochrome cH from Methylobacterium extorquens

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

See Also

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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