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Cryptochrome
From Proteopedia
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== Function == | == Function == | ||
| - | Cryptochrome (Cry) is a flavoprotein associated with the biological clock function. In ''Drosophila melanogaster'' it is also involved in blue-light photoreception<ref>PMID:18399544</ref>. | + | '''Cryptochrome''' (Cry) is a flavoprotein associated with the biological clock function. In ''Drosophila melanogaster'' it is also involved in blue-light photoreception<ref>PMID:18399544</ref>. |
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| + | For details on cryptochrome 4 see [[Cryptochrome 4]]. | ||
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| + | See also [[JMS/cryptochrome]] and [[Period circadian protein]]. | ||
== Disease == | == Disease == | ||
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</StructureSection> | </StructureSection> | ||
| - | == 3D Structures of cryptochrome == | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
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| - | [[4i6e]], [[4k0r]], [[5t5x]] – mCry-1 – mouse <br /> | ||
| - | [[4jzy]], [[4gu5]], [[4k03]] – Cry-1 + FAD – ''Drosophila melanogaster'' <br /> | ||
| - | [[1u3c]] – AtCry-1 PHR domain + FAD - ''Arabidopsis thaliana''<br /> | ||
| - | [[1u3d]] – AtCry-1 PHR domain + FAD + AMPPNP<br /> | ||
| - | [[4ct0]] – mCry-1 + PER2 <br /> | ||
| - | [[4i6g]] – mCry-2 + FAD <br /> | ||
| - | [[4i6j]] – mCry-2 + F-box/LRR repeat protein + S-phase kinase-associated protein <br /> | ||
| - | [[4u8h]] – mCry-2 + PER2 <br /> | ||
| - | [[4mlp]] – mCry-2 + carbazol derivative <br /> | ||
| - | [[3zxs]] – Cry-2 + FAD – ''Rhodobacter sphaeroides'' <br /> | ||
| - | [[2j4d]], [[2ijg]] – AtCry-3 + FAD <br /> | ||
| - | [[2vtb]] – AtCry-3 + FAD + DNA<br /> | ||
| - | [[3fy4]] – AtCry 6-4 + FAD <br /> | ||
| - | [[1np7]] – Cry - ''Synechocystis'' <br /> | ||
| - | [[6fn3]], [[5zm0]] – CrCry + FAD – ''Chlamydomonas reinhardtii''<br /> | ||
| - | [[6fn2]] – CrCry + FAD + alloxazine derivative <br /> | ||
| - | [[6fn0]] – CrCry + FAD + DNA + pyrimidine derivative <br /> | ||
== References == | == References == | ||
Current revision
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References
- ↑ Yoshii T, Todo T, Wulbeck C, Stanewsky R, Helfrich-Forster C. Cryptochrome is present in the compound eyes and a subset of Drosophila's clock neurons. J Comp Neurol. 2008 Jun 20;508(6):952-66. doi: 10.1002/cne.21702. PMID:18399544 doi:http://dx.doi.org/10.1002/cne.21702
- ↑ Narasimamurthy R, Hatori M, Nayak SK, Liu F, Panda S, Verma IM. Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12662-7. doi:, 10.1073/pnas.1209965109. Epub 2012 Jul 9. PMID:22778400 doi:http://dx.doi.org/10.1073/pnas.1209965109
