CutA1

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<StructureSection load='1uku' size='350' side='right' caption='CutA1 complex with copper (PDB entry [[1uku]])' scene='50/508403/Cv/1'>
<StructureSection load='1uku' size='350' side='right' caption='CutA1 complex with copper (PDB entry [[1uku]])' scene='50/508403/Cv/1'>
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'''CutA1''' is involved in copper tolerance in ''E. coli''. In mammals it is implicated in the anchoring of acetylcholinesterase in the neural cell membrane. The thermostability of CutA1 from ''Pyrococcus horikoshii'' is extremely high.<ref>PMID:14706845</ref> See [[Divalent cation tolerant protein CUTA from Homo sapiens O60888]].
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'''CutA1''' or '''periplasmic divalent cation tolerance protein''' is involved in copper tolerance in ''E. coli''. In mammals it is implicated in the anchoring of acetylcholinesterase in the neural cell membrane. The thermostability of CutA1 from ''Pyrococcus horikoshii'' is extremely high.<ref>PMID:14706845</ref> See [[Divalent cation tolerant protein CUTA from Homo sapiens O60888]].
== Structural highlights ==
== Structural highlights ==
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</StructureSection>
</StructureSection>
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==3D structures of CutA1==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*CutA1
 
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**[[1kr4]], [[1o5j]], [[1vhf]] – TmCutA – ''Thermotoga maritima''<br />
 
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**[[1nza]], [[1v6h]] – TtCutA – ''Thermus thermophilus''<br />
 
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**[[1p1l]] – CutA – ''Archaeoglobus fulgidus''<br />
 
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**[[1naq]], [[3x3u]] – EcCutA – ''Escherichia coli''<br />
 
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**[[3aa8]], [[3aa9]], [[3ah6]],[[4y65]], [[4y6i]] - EcCutA (mutant)<br />
 
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**[[1osc]] – CutA – rat<br />
 
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**[[1xk8]], [[2zfh]] – CutA – human<br />
 
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**[[2zom]] - CutA - rice<br />
 
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**[[1j2v]] – PhCutA – ''Pyrococcus horikoshii''<br />
 
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**[[3gsd]] - CutA – ''Yersinia pestis''<br />
 
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**[[3opk]] - CutA – ''Salmonella enterica''<br />
 
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**[[2e66]] - PhCutA (mutant)<br />
 
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**[[3ahp]] – CutA – ''Shewanella''<br />
 
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**[[4iyq]] – CutA – ''Ehrlichia chaffeensis''<br />
 
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**[[4e98]] – CutA – ''Cryptosporidium parvum''<br />
 
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*CutA1 binary complex
 
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**[[1uku]], [[4nyo]] – PhCutA + Cu<br />
 
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**[[4nyp]] - PhCutA + Co<br />
 
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**[[1umj]] - PhCutA + guanidine<br />
 
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**[[4zk7]] – TtCutA + chorismate mutase<br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

CutA1 complex with copper (PDB entry 1uku)

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References

  1. Tanaka Y, Tsumoto K, Nakanishi T, Yasutake Y, Sakai N, Yao M, Tanaka I, Kumagai I. Structural implications for heavy metal-induced reversible assembly and aggregation of a protein: the case of Pyrococcus horikoshii CutA. FEBS Lett. 2004 Jan 2;556(1-3):167-74. PMID:14706845

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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