6k15
From Proteopedia
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(New page: '''Unreleased structure''' The entry 6k15 is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==RSC substrate-recruitment module== | |
| + | <SX load='6k15' size='340' side='right' viewer='molstar' caption='[[6k15]], [[Resolution|resolution]] 3.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6k15]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6K15 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6k15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k15 OCA], [https://pdbe.org/6k15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6k15 RCSB], [https://www.ebi.ac.uk/pdbsum/6k15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6k15 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RSC7_YEAST RSC7_YEAST] Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. Together with HTL1, LDB7, RSC3, RSC30 components, defines a fungal-specific module within the RSC complex that plays a role in many cellular functions including the maintenance of cell wall integrity. Acidic protein important for nuclear protein localization.<ref>PMID:16204215</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Helicase 3D structures|Helicase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Cairns B]] | ||
| + | [[Category: Chen KJ]] | ||
| + | [[Category: Chen ZC]] | ||
| + | [[Category: Gao N]] | ||
| + | [[Category: Verma N]] | ||
| + | [[Category: Wu H]] | ||
| + | [[Category: Ye YP]] | ||
Current revision
RSC substrate-recruitment module
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Categories: Large Structures | Saccharomyces cerevisiae S288C | Cairns B | Chen KJ | Chen ZC | Gao N | Verma N | Wu H | Ye YP
