6opl
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human biliverdin IX beta reductase Q14R mutant: NADP complex== | |
| + | <StructureSection load='6opl' size='340' side='right'caption='[[6opl]], [[Resolution|resolution]] 1.37Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6opl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OPL FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.37Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6opl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6opl OCA], [https://pdbe.org/6opl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6opl RCSB], [https://www.ebi.ac.uk/pdbsum/6opl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6opl ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BLVRB_HUMAN BLVRB_HUMAN] Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.<ref>PMID:10620517</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Flavin reductase|Flavin reductase]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Eisenmesser | + | __TOC__ |
| - | [[Category: Paukovich | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Eisenmesser EZ]] | ||
| + | [[Category: Paukovich NA]] | ||
Current revision
Human biliverdin IX beta reductase Q14R mutant: NADP complex
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