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| - | | + | #REDIRECT [[5om9]] This PDB entry is obsolete and replaced by 5om9 |
| - | ==Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with a thiirane mechanism-based inhibitor==
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| - | <StructureSection load='4uf4' size='340' side='right'caption='[[4uf4]], [[Resolution|resolution]] 1.77Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[4uf4]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UF4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UF4 FirstGlance]. <br>
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| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=O2V:(2S)-4-METHYL-2-[(1R)-1-SULFANYLETHYL]PENTANOIC+ACID'>O2V</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uee|4uee]], [[4uef|4uef]], [[4uez|4uez]], [[5aek|5aek]]</td></tr>
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| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uf4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uf4 OCA], [http://pdbe.org/4uf4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uf4 RCSB], [http://www.ebi.ac.uk/pdbsum/4uf4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uf4 ProSAT]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[http://www.uniprot.org/uniprot/CBPA1_HUMAN CBPA1_HUMAN]] Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.<ref>PMID:8806703</ref>
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| - | ==See Also==
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| - | *[[Carboxypeptidase 3D structures|Carboxypeptidase 3D structures]]
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| - | == References ==
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| - | <references/>
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Carboxypeptidase A]]
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| - | [[Category: Large Structures]]
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| - | [[Category: Aviles, F X]]
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| - | [[Category: Covaleda, G]]
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| - | [[Category: Gallego, P]]
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| - | [[Category: Granados, C]]
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| - | [[Category: Pallares, I]]
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| - | [[Category: Reverter, D]]
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| - | [[Category: Vendrell, J]]
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| - | [[Category: Hydrolase]]
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