6p07

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(New page: '''Unreleased structure''' The entry 6p07 is ON HOLD Authors: Sandate, C.R., Szyk, A., Zehr, E., Roll-Mecak, A., Lander, G.C. Description: Spastin hexamer in complex with substrate [[C...)
Current revision (09:25, 20 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 6p07 is ON HOLD
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==Spastin hexamer in complex with substrate==
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<SX load='6p07' size='340' side='right' viewer='molstar' caption='[[6p07]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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Authors: Sandate, C.R., Szyk, A., Zehr, E., Roll-Mecak, A., Lander, G.C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6p07]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P07 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6P07 FirstGlance]. <br>
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Description: Spastin hexamer in complex with substrate
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Zehr, E]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6p07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p07 OCA], [https://pdbe.org/6p07 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6p07 RCSB], [https://www.ebi.ac.uk/pdbsum/6p07 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6p07 ProSAT]</span></td></tr>
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[[Category: Roll-Mecak, A]]
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</table>
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[[Category: Szyk, A]]
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== Function ==
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[[Category: Lander, G.C]]
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[https://www.uniprot.org/uniprot/A0A0B4LHJ5_DROME A0A0B4LHJ5_DROME] ATP-dependent microtubule severing protein. Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle. Regulates microtubule stability in the neuromuscular junction synapse. Involved in lipid metabolism by regulating the size and distribution of lipid droplets. Involved in axon regeneration by regulating microtubule severing.[HAMAP-Rule:MF_03021]
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[[Category: Sandate, C.R]]
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__TOC__
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</SX>
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[[Category: Drosophila melanogaster]]
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[[Category: Large Structures]]
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[[Category: Lander GC]]
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[[Category: Roll-Mecak A]]
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[[Category: Sandate CR]]
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[[Category: Szyk A]]
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[[Category: Zehr E]]

Current revision

Spastin hexamer in complex with substrate

6p07, resolution 3.20Å

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