6rp3
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Truncated Norcoclaurine synthase with reaction intermediate mimic== | |
- | + | <StructureSection load='6rp3' size='340' side='right'caption='[[6rp3]], [[Resolution|resolution]] 1.81Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6rp3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thalictrum_flavum_subsp._glaucum Thalictrum flavum subsp. glaucum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RP3 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81Å</td></tr> | |
- | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=KCZ:4-[2-[[(2~{R})-2-phenylpropyl]amino]ethyl]benzene-1,2-diol'>KCZ</scene></td></tr> |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rp3 OCA], [https://pdbe.org/6rp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rp3 RCSB], [https://www.ebi.ac.uk/pdbsum/6rp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rp3 ProSAT]</span></td></tr> |
- | [[Category: Roddan | + | </table> |
- | [[Category: | + | == Function == |
+ | [https://www.uniprot.org/uniprot/NCS_THLFG NCS_THLFG] Involved in the biosynthesis of the common precursor of all benzylisoquinoline alkaloids such as morphine, sanguinarine, codeine or berberine. Condenses dopamine and 4-hydroxyphenylacetaldehyde.<ref>PMID:17696451</ref> <ref>PMID:17900926</ref> <ref>PMID:18384289</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Thalictrum flavum subsp. glaucum]] | ||
+ | [[Category: Keep NH]] | ||
+ | [[Category: Roddan R]] | ||
+ | [[Category: Sula A]] |
Current revision
Truncated Norcoclaurine synthase with reaction intermediate mimic
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