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6aaq

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Current revision (09:23, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6aaq' size='340' side='right'caption='[[6aaq]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
<StructureSection load='6aaq' size='340' side='right'caption='[[6aaq]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6aaq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanosarcina_mazei_jcm_9314 Methanosarcina mazei jcm 9314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AAQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AAQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6aaq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_mazei_JCM_9314 Methanosarcina mazei JCM 9314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AAQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AAQ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9U9:N6-({[(1R,8S,9s)-bicyclo[6.1.0]non-4-yn-9-yl]methoxy}carbonyl)-L-lysine'>9U9</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.551&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6aac|6aac]], [[6aad|6aad]], [[6aan|6aan]], [[6aao|6aao]], [[6aap|6aap]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9U9:N6-({[(1R,8S,9s)-bicyclo[6.1.0]non-4-yn-9-yl]methoxy}carbonyl)-L-lysine'>9U9</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pylS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1293038 Methanosarcina mazei JCM 9314])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6aaq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aaq OCA], [https://pdbe.org/6aaq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6aaq RCSB], [https://www.ebi.ac.uk/pdbsum/6aaq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6aaq ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyrrolysine--tRNA(Pyl)_ligase Pyrrolysine--tRNA(Pyl) ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.26 6.1.1.26] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6aaq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aaq OCA], [http://pdbe.org/6aaq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aaq RCSB], [http://www.ebi.ac.uk/pdbsum/6aaq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aaq ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PYLS_METMA PYLS_METMA]] Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG (By similarity).
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[https://www.uniprot.org/uniprot/PYLS_METMA PYLS_METMA] Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Methanosarcina mazei jcm 9314]]
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[[Category: Methanosarcina mazei JCM 9314]]
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[[Category: Kuratani, M]]
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[[Category: Kuratani M]]
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[[Category: Yanagisawa, T]]
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[[Category: Yanagisawa T]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Aminoacyl-trna synthetase]]
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[[Category: Non-natural amino acid]]
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[[Category: Translation]]
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Current revision

Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with BCNLys

PDB ID 6aaq

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