5qqs
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z275151340== | |
| - | + | <StructureSection load='5qqs' size='340' side='right'caption='[[5qqs]], [[Resolution|resolution]] 1.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5qqs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QQS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QQS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JHP:4-chloro-N-cyclopentyl-1-methyl-1H-pyrazole-3-carboxamide'>JHP</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> |
| - | [[Category: Foster | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qqs OCA], [https://pdbe.org/5qqs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qqs RCSB], [https://www.ebi.ac.uk/pdbsum/5qqs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qqs ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/HEM0_HUMAN HEM0_HUMAN] X-linked sideroblastic anemia;Erythropoietic protoporphyria. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. Gain of function mutations in ALS2 are responsible for XLDPT, but they can also be a possible aggravating factor in congenital erythropoietic porphyria and other erythropoietic disorders caused by mutations in other genes (PubMed:21309041).<ref>PMID:21309041</ref> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HEM0_HUMAN HEM0_HUMAN] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Bailey H]] | ||
| + | [[Category: Bezerra GA]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Brandao-Neto J]] | ||
| + | [[Category: Brennan PE]] | ||
| + | [[Category: Douangamath A]] | ||
| + | [[Category: Edwards A]] | ||
| + | [[Category: Foster W]] | ||
| + | [[Category: Krojer T]] | ||
| + | [[Category: Nicola BB]] | ||
[[Category: Shrestha L]] | [[Category: Shrestha L]] | ||
| - | + | [[Category: Talon R]] | |
| - | + | [[Category: Yue WW]] | |
| - | [[Category: Talon | + | [[Category: Von Delft F]] |
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| - | [[Category: Yue | + | |
| - | [[Category: Von Delft | + | |
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Current revision
PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z275151340
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bailey H | Bezerra GA | Bountra C | Brandao-Neto J | Brennan PE | Douangamath A | Edwards A | Foster W | Krojer T | Nicola BB | Shrestha L | Talon R | Yue WW | Von Delft F
