6jbj

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'''Unreleased structure'''
 
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The entry 6jbj is ON HOLD until Paper Publication
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==Cryo-EM structure of human lysosomal cobalamin exporter ABCD4==
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<SX load='6jbj' size='340' side='right' viewer='molstar' caption='[[6jbj]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6jbj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JBJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JBJ FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jbj OCA], [https://pdbe.org/6jbj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jbj RCSB], [https://www.ebi.ac.uk/pdbsum/6jbj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jbj ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/ABCD4_HUMAN ABCD4_HUMAN] Methylmalonic acidemia with homocystinuria, type cblJ. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/ABCD4_HUMAN ABCD4_HUMAN] May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm.<ref>PMID:22922874</ref>
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== References ==
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<references/>
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__TOC__
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</SX>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chen Y]]
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[[Category: Feng Z]]
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[[Category: Hou WT]]
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[[Category: Jiang YL]]
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[[Category: Sun LF]]
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[[Category: Wang L]]
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[[Category: Xu D]]
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[[Category: Zhou CZ]]

Current revision

Cryo-EM structure of human lysosomal cobalamin exporter ABCD4

6jbj, resolution 3.60Å

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