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5zx9
From Proteopedia
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| - | ==Crystal structure of | + | ==Crystal structure of apo form fibronectin-binding protein Apa from Mycobacterium tuberculosis== |
<StructureSection load='5zx9' size='340' side='right'caption='[[5zx9]], [[Resolution|resolution]] 1.55Å' scene=''> | <StructureSection load='5zx9' size='340' side='right'caption='[[5zx9]], [[Resolution|resolution]] 1.55Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5zx9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZX9 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5zx9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZX9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZX9 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zx9 OCA], [https://pdbe.org/5zx9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zx9 RCSB], [https://www.ebi.ac.uk/pdbsum/5zx9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zx9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/APA_MYCTU APA_MYCTU] A potent antigen in animals immunized with live bacteria, it induces a strong delayed-type hypersensitivity (DTH) in immunized animals (PubMed:10531201). Elicits a mostly Th1 type of T-cell response in healthy humans; induces IFN-gamma production from CD4(+) and CD8(+) cells (PubMed:12654810). Functions as an adhesin, binds to mouse macrophages via mannose residues (PubMed:10531201, PubMed:25359607). Might interact via host CD209 (PubMed:16092920).<ref>PMID:10531201</ref> <ref>PMID:12654810</ref> <ref>PMID:16092920</ref> <ref>PMID:25359607</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
| - | [[Category: | + | [[Category: Chen CC]] |
| - | [[Category: | + | [[Category: Gao J]] |
| - | [[Category: | + | [[Category: Guo RT]] |
| - | [[Category: | + | [[Category: Liu WD]] |
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Current revision
Crystal structure of apo form fibronectin-binding protein Apa from Mycobacterium tuberculosis
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