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Defensin
From Proteopedia
(Difference between revisions)
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</StructureSection> | </StructureSection> | ||
| - | ==3D structures of defensin== | ||
| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | *α-defensin | ||
| - | |||
| - | **[[1ica]] – DEFA – ''Protophormia terraenovae''<BR /> | ||
| - | **[[1ews]] – DEFA RK-1 – rabbit – NMR<BR /> | ||
| - | **[[2k1i]] - RmDEFA – Rhesus macaque - NMR<BR /> | ||
| - | **[[1zmh]], [[1zmi]], [[1zmk]] - hDEFA HNP-2 (mutant) – human<BR /> | ||
| - | **[[3gny]], [[3go0]], [[3hj2]] - hDEFA HNP-1<BR /> | ||
| - | **[[2kht]] - hDEFA HNP-1 - NMR<BR /> | ||
| - | **[[2pm1]], [[2pm4]], [[2pm5]], [[3hjd]], [[3h6c]], [[3lo1]], [[3lo2]], [[3lo4]], [[3lo6]], [[3lo8]], [[3loe]], [[3lvx]], [[4du0]], [[4lb1]], [[4lb7]], [[4lbb]], [[4lbf]] - hDEFA HNP-1 (mutant) <BR /> | ||
| - | **[[1zmm]] – hDEFA4 <BR /> | ||
| - | **[[2lew]] – mDEFA4 (mutant) – mouse – NMR<br /> | ||
| - | **[[2ley]] – mDEFA4 – NMR<br /> | ||
| - | **[[1zmp]] – hDEFA5<BR /> | ||
| - | **[[2lxz]] – hDEFA5 – NMR<br /> | ||
| - | **[[3i5w]], [[4e82]], [[4e83]], [[4e86]] – hDEFA5 (mutant) <BR /> | ||
| - | **[[1zmq]] – hDEFA6<BR /> | ||
| - | **[[3qte]] – hDEFA6 (mutant) | ||
| - | |||
| - | *β-defensin | ||
| - | |||
| - | **[[1iju]], [[1ijv]] – hDEFB1<BR /> | ||
| - | **[[2nlb]], [[2nld]], [[2nle]], [[2nlf]], [[2nlg]], [[2nlh]], [[2nlp]], [[2nlq]], [[2nls]], [[2plz]], [[2lwl]], [[2nlc]] - hDEFB1 (mutant) <BR /> | ||
| - | **[[1e4s]], [[1kj5]] – hDEFB1 – NMR<BR /> | ||
| - | **[[1fd3]], [[1fd4]] – hDEFB2 <BR /> | ||
| - | **[[1fqq]], [[1e4q]] - hDEFB2 – NMR<BR /> | ||
| - | **[[2lg5]] - cDEFB2 – chicken – NMR<BR /> | ||
| - | **[[2lg6]] - cDEFB2 (mutant) – NMR<BR /> | ||
| - | **[[1kj6]] – hDEFB3 – NMR<BR /> | ||
| - | **[[5ki9]] – hDEFB4<br /> | ||
| - | **[[6cs9]] – hDEFB4A + PIP2<br /> | ||
| - | **[[1e4t]] – mDEFB7 – NMR<BR /> | ||
| - | **[[1e4r]] - mDEFB8 – NMR<BR /> | ||
| - | **[[1bnb]] – DEFB12 – bovine – NMR<BR /> | ||
| - | |||
| - | *ϑ-defensin | ||
| - | |||
| - | **[[1hvz]] – RmDEF1 – NMR<BR /> | ||
| - | **[[5inz]] – DEF2 - baboon<br /> | ||
| - | |||
| - | *Defensin-1 | ||
| - | |||
| - | **[[3lo9]] – hDEF1 (mutant)<br /> | ||
| - | **[[5nce]] – DEF1 – pine - NMR<br /> | ||
| - | **[[6b9w]], [[6bam]], [[6bb6]], [[6bi5]] – DEF1 – mexican scorpion - NMR<br /> | ||
| - | |||
| - | *Defensin-2 | ||
| - | |||
| - | **[[2gl1]] – VrDEF2 - ''Vigna radiata''<br /> | ||
| - | |||
| - | *Defensin-4 | ||
| - | |||
| - | **[[6dmm]], [[6dmq]] – hDEF4 (mutant)<br /> | ||
| - | |||
| - | *Defensin-5 | ||
| - | |||
| - | **[[5cui]], [[5cuj]], [[5cum]] – hDEF5 (mutant)<br /> | ||
| - | **[[2mit]] – hDEF5 – NMR<br /> | ||
| - | **[[4rbw]], [[4rbx]] – hDEF5 (mutant) – NMR<br /> | ||
| - | **[[2ksk]] – DEF5 – Sugarcane – NMR<br /> | ||
| - | |||
| - | *Defensin | ||
| - | |||
| - | |||
| - | *Other defensins | ||
| - | |||
| - | **[[1dfn]] – hDEF HNP-3 <BR /> | ||
| - | **[[1fjn]] – DEF MGD-1 – Mediterranean mussel<BR /> | ||
| - | **[[1mr4]] – tDEF NAD1 – tobacco – NMR<BR /> | ||
| - | **[[4aaz]], [[4ab0]] - tDEF NAD1<BR /> | ||
| - | **[[4cqk]] - tDEF NAD1 + ligand<br /> | ||
| - | **[[5vyp]] - tDEF NSD7<br /> | ||
| - | **[[5kk4]] - tDEF NSD7 + phosphatidic acid<br /> | ||
| - | **[[1ozz]] – AdDEF ARD1 – ''Archaeoprepona demophon'' – NMR<BR /> | ||
| - | **[[1p00]], [[1p0a]] - AdDEF ARD1 (mutant) – NMR<BR /> | ||
| - | **[[1ti5]] - VrDEF – NMR<BR /> | ||
| - | **[[2b68]] - DEF – Pacific oyster – NMR<BR /> | ||
| - | **[[2b5b]] - DEF – Loggerhead turtle – NMR<BR /> | ||
| - | **[[2e3e]], [[2e3f]], [[2e3g]], [[2ny8]], [[2ny9]], [[2nz3]] - DEF (mutant) – Anopheles – NMR<BR /> | ||
| - | **[[2rng]] - DEF – Horseshoe crab – NMR<BR /> | ||
| - | **[[3psm]] – DEF – Potato bean<BR /> | ||
| - | **[[2lj7]] – DEF – lentil – NMR<br /> | ||
| - | **[[2lr3]] – DEF – barrel medic – NMR<br /> | ||
| - | **[[6mry]] - DEF NOD173 – ''Nicotiana occidentalis''<br /> | ||
| - | **[[6b55]] - DEF – ''Nicotiana alata''<br /> | ||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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References
- ↑ White SH, Wimley WC, Selsted ME. Structure, function, and membrane integration of defensins. Curr Opin Struct Biol. 1995 Aug;5(4):521-7. PMID:8528769
- ↑ Ganz T, Selsted ME, Szklarek D, Harwig SS, Daher K, Bainton DF, Lehrer RI. Defensins. Natural peptide antibiotics of human neutrophils. J Clin Invest. 1985 Oct;76(4):1427-35. PMID:2997278 doi:http://dx.doi.org/10.1172/JCI112120
- ↑ Zhuravel OV, Gerashchenko OL, Khetsuriani MR, Soldatkina MA, Pogrebnoy PV. Expression of human beta-defensins-1-4 in thyroid cancer cells and new insight on biologic activity of hBD-2 in vitro. Exp Oncol. 2014 Sep;36(3):174-8. PMID:25265350
