5qsq

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m (Protected "5qsq" [edit=sysop:move=sysop])
Current revision (11:26, 21 February 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5qsq is ON HOLD
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==PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z396380540==
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<StructureSection load='5qsq' size='340' side='right'caption='[[5qsq]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
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Authors: Newman, J.A., Katis, V.L., Gavard, A.E., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5qsq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QSQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QSQ FirstGlance]. <br>
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Description: PanDDA analysis group deposition --Crystal Structure of human STAG1 in complex with Z396380540
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.48&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HR5:~{N}-(cyclobutylmethyl)-1,5-dimethyl-pyrazole-4-carboxamide'>HR5</scene></td></tr>
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[[Category: Katis, V.L]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qsq OCA], [https://pdbe.org/5qsq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qsq RCSB], [https://www.ebi.ac.uk/pdbsum/5qsq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qsq ProSAT]</span></td></tr>
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[[Category: Arrowsmith, C.H]]
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</table>
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[[Category: Gileadi, O]]
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== Disease ==
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[[Category: Newman, J.A]]
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[https://www.uniprot.org/uniprot/STAG1_HUMAN STAG1_HUMAN] STAG1-related intellectual disability-facial dysmorphism-gastroesophageal reflux syndrome. The disease is caused by mutations affecting the gene represented in this entry.
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[[Category: Edwards, A]]
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== Function ==
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[[Category: Gavard, A.E]]
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[https://www.uniprot.org/uniprot/STAG1_HUMAN STAG1_HUMAN] Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
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[[Category: Von Delft, F]]
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__TOC__
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[[Category: Bountra, C]]
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra C]]
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[[Category: Edwards A]]
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[[Category: Gavard AE]]
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[[Category: Gileadi O]]
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[[Category: Katis VL]]
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[[Category: Newman JA]]
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[[Category: Von Delft F]]

Current revision

PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z396380540

PDB ID 5qsq

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