6p1k
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Cryo-EM structure of Escherichia coli sigma70 bound RNAP polymerase holoenzyme== | |
+ | <SX load='6p1k' size='340' side='right' viewer='molstar' caption='[[6p1k]], [[Resolution|resolution]] 4.05Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[6p1k]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P1K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6P1K FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.05Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6p1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p1k OCA], [https://pdbe.org/6p1k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6p1k RCSB], [https://www.ebi.ac.uk/pdbsum/6p1k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6p1k ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059] | ||
- | + | ==See Also== | |
- | + | *[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | |
- | + | *[[Sigma factor 3D structures|Sigma factor 3D structures]] | |
- | [[Category: | + | __TOC__ |
+ | </SX> | ||
+ | [[Category: Escherichia coli]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Campbell EA]] | ||
+ | [[Category: Chen J]] | ||
+ | [[Category: Chiu CE]] | ||
+ | [[Category: Darst SA]] |
Current revision
Cryo-EM structure of Escherichia coli sigma70 bound RNAP polymerase holoenzyme
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