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6cn8
From Proteopedia
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<StructureSection load='6cn8' size='340' side='right'caption='[[6cn8]], [[Resolution|resolution]] 1.40Å' scene=''> | <StructureSection load='6cn8' size='340' side='right'caption='[[6cn8]], [[Resolution|resolution]] 1.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6cn8]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6cn8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] and [https://en.wikipedia.org/wiki/Streptomyces_atratus Streptomyces atratus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CN8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CN8 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=F7P:1-[(3R)-3-hydroxy-2-methylbutan-2-yl]-L-tryptophan'>F7P</scene>, <scene name='pdbligand=F7S:(4S)-5-hydroxy-N-methyl-L-leucine'>F7S</scene>, <scene name='pdbligand=F7V:(2S,4E)-2-aminohex-4-enoic+acid'>F7V</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NIY:META-NITRO-TYROSINE'>NIY</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cn8 OCA], [https://pdbe.org/6cn8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cn8 RCSB], [https://www.ebi.ac.uk/pdbsum/6cn8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cn8 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CLPC1_MYCTU CLPC1_MYCTU] ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity). Degrades anti-sigma-E factor RseA in the presence of ClpP2. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 6cn8" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6cn8" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Clp protease 3D structures|Clp protease 3D structures]] | ||
| + | *[[Heat Shock Protein structures|Heat Shock Protein structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Streptomyces atratus]] | ||
| - | [[Category: Abad-Zapatero, C]] | ||
| - | [[Category: Wolf, N W]] | ||
| - | [[Category: Atp-dependent protease]] | ||
| - | [[Category: Atpase aaa+]] | ||
| - | [[Category: Chaperone]] | ||
| - | [[Category: Chaperone-antibiotic complex]] | ||
| - | [[Category: Clpc1-ntd]] | ||
| - | [[Category: Macrocyclic peptide]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | [[Category: | + | [[Category: Streptomyces atratus]] |
| - | [[Category: | + | [[Category: Abad-Zapatero C]] |
| + | [[Category: Wolf NW]] | ||
Current revision
High-resolution structure of ClpC1-NTD binding to Rufomycin-I
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