User:Michael Scott Thomas/Sandbox 2
From Proteopedia
< User:Michael Scott Thomas(Difference between revisions)
| (14 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | == | + | == GC receptor shenanigans== |
<StructureSection load='3bqd' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='3bqd' size='340' side='right' caption='Caption for this structure' scene=''> | ||
This is a default text for your page '''Michael Scott Thomas/Sandbox 2'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page '''Michael Scott Thomas/Sandbox 2'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
| Line 6: | Line 6: | ||
== Important Bonds == | == Important Bonds == | ||
| - | <scene name='81/817570/Newarg611/ | + | <scene name='81/817570/Newarg611/6'>R611</scene> |
<scene name='81/817570/Newgln570/3'>Q570</scene> | <scene name='81/817570/Newgln570/3'>Q570</scene> | ||
<scene name='81/817570/A607/5'>A607</scene> | <scene name='81/817570/A607/5'>A607</scene> | ||
| + | <scene name='81/817570/Leu608/1'>L608</scene> | ||
| + | <scene name='81/817570/Met604/1'>M604</scene> | ||
== Binding Pocket == | == Binding Pocket == | ||
| - | <scene name='81/817570/Grbindingpocket1/ | + | <scene name='81/817570/Grbindingpocket1/3'>Attempt at showing the binding pocket</scene> |
| + | == Interpreting Synthetic Glucocorticoid Kds == | ||
| - | + | <scene name='81/817570/Interpretingdpa/1'>DPA</scene> has the highest kd (bad binding affinity). | |
| + | [[Image:Dpachemdraw.png]] | ||
| + | [[Image:Betterdpapic.png]] | ||
| + | |||
| + | DPFB... Has the smallest kd (best binding affinity). | ||
| + | [[Image:DPFBchemdraw.png]] | ||
| + | [[Image:DPFBpic.png]] | ||
| + | |||
| + | == Predicting Synthetic Glucocortioid Kds == | ||
| + | PYR2 we know nothing about this guys kd. | ||
| + | [[Image:PYR2chemdraw.png]] | ||
| + | [[Image:PYR2.png]] | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Current revision
GC receptor shenanigans
| |||||||||||
References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644






