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6j8n
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of SVBP-VASH1 complex, mutation C169A of VASH1== | |
| + | <StructureSection load='6j8n' size='340' side='right'caption='[[6j8n]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6j8n]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J8N FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j8n OCA], [https://pdbe.org/6j8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j8n RCSB], [https://www.ebi.ac.uk/pdbsum/6j8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j8n ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SVBP_HUMAN SVBP_HUMAN] Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin (PubMed:29146869). Also required to enhance the solubility and secretion of VASH1 and VASH2 (PubMed:20736312, PubMed:27879017).<ref>PMID:20736312</ref> <ref>PMID:27879017</ref> <ref>PMID:29146869</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Carboxypeptidase 3D structures|Carboxypeptidase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gao J]] | ||
| + | [[Category: Liao S]] | ||
| + | [[Category: Xu C]] | ||
Current revision
Crystal structure of SVBP-VASH1 complex, mutation C169A of VASH1
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Categories: Homo sapiens | Large Structures | Gao J | Liao S | Xu C
