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5iki

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Current revision (13:58, 30 August 2023) (edit) (undo)
 
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<StructureSection load='5iki' size='340' side='right'caption='[[5iki]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='5iki' size='340' side='right'caption='[[5iki]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5iki]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_14581 Atcc 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IKI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5iki]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium Priestia megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IKI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IKI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A9H:ABIETIC+ACID'>A9H</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yt3|4yt3]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A9H:ABIETIC+ACID'>A9H</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cyp106A2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1404 ATCC 14581])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iki OCA], [https://pdbe.org/5iki PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iki RCSB], [https://www.ebi.ac.uk/pdbsum/5iki PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iki ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iki OCA], [http://pdbe.org/5iki PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iki RCSB], [http://www.ebi.ac.uk/pdbsum/5iki PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iki ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CPXM_BACME CPXM_BACME]] Has the capacity to hydroxylate certain steroids in the 15-beta position. Also hydroxylates progesterone in the 11-alpha and 9-beta position.<ref>PMID:18481342</ref>
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[https://www.uniprot.org/uniprot/CPXM_PRIMG CPXM_PRIMG] Has the capacity to hydroxylate certain steroids in the 15-beta position. Also hydroxylates progesterone in the 11-alpha and 9-beta position.<ref>PMID:18481342</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 14581]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bernhardt, R]]
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[[Category: Priestia megaterium]]
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[[Category: Carius, Y]]
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[[Category: Bernhardt R]]
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[[Category: Janocha, S]]
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[[Category: Carius Y]]
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[[Category: Lancaster, C R.D]]
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[[Category: Janocha S]]
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[[Category: 15-beta-hydroxylase]]
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[[Category: Lancaster CRD]]
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[[Category: Cytochrome p450]]
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[[Category: Mono-oxygenase]]
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[[Category: Oxidoreductase]]
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Current revision

CYP106A2 WITH SUBSTRATE ABIETIC ACID

PDB ID 5iki

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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