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6nwa

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==The structure of the photosystem I IsiA super-complex==
==The structure of the photosystem I IsiA super-complex==
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<StructureSection load='6nwa' size='340' side='right'caption='[[6nwa]], [[Resolution|resolution]] 3.48&Aring;' scene=''>
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<SX load='6nwa' size='340' side='right' viewer='molstar' caption='[[6nwa]], [[Resolution|resolution]] 3.48&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6nwa]] is a 51 chain structure with sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp._pcc_6803 Synechocystis sp. pcc 6803]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NWA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6nwa]] is a 45 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechocystis_sp._PCC_6803 Synechocystis sp. PCC 6803]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NWA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCR:BETA-CAROTENE'>BCR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL0:CHLOROPHYLL+A+ISOMER'>CL0</scene>, <scene name='pdbligand=CLA:CHLOROPHYLL+A'>CLA</scene>, <scene name='pdbligand=LHG:1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE'>LHG</scene>, <scene name='pdbligand=LMG:1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE'>LMG</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=PQN:PHYLLOQUINONE'>PQN</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.48&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Photosystem_I Photosystem I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.97.1.12 1.97.1.12] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCR:BETA-CAROTENE'>BCR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL0:CHLOROPHYLL+A+ISOMER'>CL0</scene>, <scene name='pdbligand=CLA:CHLOROPHYLL+A'>CLA</scene>, <scene name='pdbligand=LHG:1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE'>LHG</scene>, <scene name='pdbligand=LMG:1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE'>LMG</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=PQN:PHYLLOQUINONE'>PQN</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nwa OCA], [http://pdbe.org/6nwa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nwa RCSB], [http://www.ebi.ac.uk/pdbsum/6nwa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nwa ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nwa OCA], [https://pdbe.org/6nwa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nwa RCSB], [https://www.ebi.ac.uk/pdbsum/6nwa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nwa ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ISIA_SYNY3 ISIA_SYNY3]] Functions as an antenna for photosystem I (PSI) under iron-limiting conditions, when phycobilisomes disappear. In the (PSI)3(Isi3)18 complex most of the harvested energy is probably used by PSI; in other PSI-containing supercomplexes a large part of the energy will probably not be used for light harvesting, but rather is dissipated to protect the organism from light damage.<ref>PMID:11507643</ref> <ref>PMID:16086587</ref> [[http://www.uniprot.org/uniprot/PSAE_SYNY3 PSAE_SYNY3]] Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.[HAMAP-Rule:MF_00613]
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[https://www.uniprot.org/uniprot/PSAD_SYNY3 PSAD_SYNY3]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Photochemical conversion in oxygenic photosynthesis takes place in two large protein-pigment complexes named photosystem II and photosystem I (PSII and PSI, respectively). Photosystems associate with antennae in vivo to increase the size of photosynthetic units to hundreds or thousands of pigments. Regulation of the interactions between antennae and photosystems allows photosynthetic organisms to adapt to their environment. In low-iron environments, cyanobacteria express IsiA, a PSI antenna, critical to their survival. Here we describe the structure of the PSI-IsiA complex isolated from the mesophilic cyanobacterium Synechocystis sp. PCC 6803. This 2-MDa photosystem-antenna supercomplex structure reveals more than 700 pigments coordinated by 51 subunits, as well as the mechanisms facilitating the self-assembly and association of IsiA with multiple PSI assemblies.
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The structure of the stress-induced photosystem I-IsiA antenna supercomplex.,Toporik H, Li J, Williams D, Chiu PL, Mazor Y Nat Struct Mol Biol. 2019 Jun;26(6):443-449. doi: 10.1038/s41594-019-0228-8. Epub, 2019 May 27. PMID:31133699<ref>PMID:31133699</ref>
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==See Also==
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*[[Photosystem I 3D structures|Photosystem I 3D structures]]
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 6nwa" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
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</StructureSection>
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</SX>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Photosystem I]]
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[[Category: Synechocystis sp. PCC 6803]]
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[[Category: Synechocystis sp. pcc 6803]]
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[[Category: Chiu PL]]
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[[Category: Chiu, P L]]
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[[Category: Li J]]
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[[Category: Li, J]]
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[[Category: Mazor Y]]
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[[Category: Mazor, Y]]
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[[Category: Toporik H]]
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[[Category: Toporik, H]]
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[[Category: Williams D]]
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[[Category: Williams, D]]
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[[Category: Antenna]]
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[[Category: Chlorophyll]]
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[[Category: Membrane]]
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[[Category: Photosynthesis]]
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[[Category: Photosystem]]
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Current revision

The structure of the photosystem I IsiA super-complex

6nwa, resolution 3.48Å

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