3bwp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px <!-- The line below this paragraph, containing "STRUCTURE_3bwp", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...)
Current revision (09:31, 21 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3bwp.jpg|left|200px]]
 
-
<!--
+
==Crystal structure of a self-spliced group II intron==
-
The line below this paragraph, containing "STRUCTURE_3bwp", creates the "Structure Box" on the page.
+
<StructureSection load='3bwp' size='340' side='right'caption='[[3bwp]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3bwp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oceanobacillus_iheyensis Oceanobacillus iheyensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BWP FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
{{STRUCTURE_3bwp| PDB=3bwp | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bwp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwp OCA], [https://pdbe.org/3bwp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bwp RCSB], [https://www.ebi.ac.uk/pdbsum/3bwp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bwp ProSAT]</span></td></tr>
-
 
+
</table>
-
'''Crystal structure of a self-spliced group II intron'''
+
__TOC__
-
 
+
</StructureSection>
-
 
+
[[Category: Large Structures]]
-
==Overview==
+
[[Category: Oceanobacillus iheyensis]]
-
Group II introns are self-splicing ribozymes that catalyze their own excision from precursor transcripts and insertion into new genetic locations. Here we report the crystal structure of an intact, self-spliced group II intron from Oceanobacillus iheyensis at 3.1 angstrom resolution. An extensive network of tertiary interactions facilitates the ordered packing of intron subdomains around a ribozyme core that includes catalytic domain V. The bulge of domain V adopts an unusual helical structure that is located adjacent to a major groove triple helix (catalytic triplex). The bulge and catalytic triplex jointly coordinate two divalent metal ions in a configuration that is consistent with a two-metal ion mechanism for catalysis. Structural and functional analogies support the hypothesis that group II introns and the spliceosome share a common ancestor.
+
[[Category: Keating KS]]
-
 
+
[[Category: Pyle AM]]
-
==About this Structure==
+
[[Category: Taylor SD]]
-
3BWP is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWP OCA].
+
[[Category: Toor N]]
-
 
+
-
==Reference==
+
-
Crystal structure of a self-spliced group II intron., Toor N, Keating KS, Taylor SD, Pyle AM, Science. 2008 Apr 4;320(5872):77-82. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18388288 18388288]
+
-
[[Category: Single protein]]
+
-
[[Category: Keating, K S.]]
+
-
[[Category: Pyle, A M.]]
+
-
[[Category: Taylor, S D.]]
+
-
[[Category: Toor, N.]]
+
-
[[Category: Group ii]]
+
-
[[Category: Intron]]
+
-
[[Category: Ribonucleic acid]]
+
-
[[Category: Rna]]
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 16 23:13:05 2008''
+

Current revision

Crystal structure of a self-spliced group II intron

PDB ID 3bwp

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools