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Epoxide hydrolase 3D structures

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(New page: == 3D Structures of epoxide hydrolase== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Epoxide hydrolase **[[2e...)
Current revision (08:35, 23 February 2023) (edit) (undo)
 
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Line 6: Line 6:
*Epoxide hydrolase
*Epoxide hydrolase
-
**[[2e3j]] – EH B – ''Mycobacterium tuberculosis''<br />
+
**[[4qla]] – EH – silkworm<br />
-
**[[1qo7]], [[3g02]] – AnEH (mutant) – ''Aspergillus niger''<br />
+
**[[2cjp]] – pEH I – potato<br />
**[[2cjp]] – pEH I – potato<br />
**[[3cxu]], [[4ufn]], [[4ufo]], [[4ufp]], [[4uhb]], [[4y9s]] – pEH (mutant) <br />
**[[3cxu]], [[4ufn]], [[4ufo]], [[4ufp]], [[4uhb]], [[4y9s]] – pEH (mutant) <br />
-
**[[4i19]], [[4qa9]], [[5f4z]] – EH – ''Streptomyces carzinostaticus''<br />
 
-
**[[4qla]] – EH – silkworm<br />
 
-
**[[5cxo]] – EH – ''Streptomyces albus''<br />
 
-
**[[5nfq]], [[5ng7]] – EH – metagenome<br />
 
**[[5xmd]] – mbEH – mung bean<br />
**[[5xmd]] – mbEH – mung bean<br />
**[[5y6y]], [[5y5d]], [[5xm6]] – mbEH (mutant)<br />
**[[5y6y]], [[5y5d]], [[5xm6]] – mbEH (mutant)<br />
 +
**[[2e3j]] – MtEH B – ''Mycobacterium tuberculosis''<br />
 +
**[[5cw2]] – EH A – ''Mycobacterium thermoresistibile<''br />
 +
**[[1qo7]], [[3g02]] – AnEH (mutant) – ''Aspergillus niger''<br />
 +
**[[6ix4]] – AuEH – ''Aspergillus usamii''<br />
 +
**[[6ix2]] – AuSEH (mutant) <br />
 +
**[[4i19]], [[4qa9]], [[5f4z]] – EH – ''Streptomyces carzinostaticus''<br />
 +
**[[5cxo]], [[6unw]] – EH – ''Streptomyces albus''<br />
 +
**[[5nfq]], [[5ng7]] – meEH – metagenome<br />
 +
**[[7cg2]], [[7cg6]] – EH (mutant) – ''Vigna radiata''<br />
-
*Soluble epoxide hydrolase
+
*Soluble epoxide hydrolase or bifunctional epoxide hydrolase 2
**[[1s8o]], [[3i1y]], [[3i28]], [[3koo]], [[5ahx]], [[5fp0]] – hSEH – human<br />
**[[1s8o]], [[3i1y]], [[3i28]], [[3koo]], [[5ahx]], [[5fp0]] – hSEH – human<br />
Line 26: Line 30:
**[[1ehy]] – SEH – ''Agrobacterium tumefaciens''<br />
**[[1ehy]] – SEH – ''Agrobacterium tumefaciens''<br />
-
*Epoxide hydrolase complex with inhibitor
+
*Epoxide hydrolase complex with inhibitor; Domains: catalytic 222-555
 +
**[[5yb5]] – mbEH (mutant) + styrene derivative<br />
**[[3g0i]] – AnEH + valpromide<br />
**[[3g0i]] – AnEH + valpromide<br />
**[[3rga]] – SlEH + oxazolidinone inhibitor – ''Streptomyces lasaliensis''<br />
**[[3rga]] – SlEH + oxazolidinone inhibitor – ''Streptomyces lasaliensis''<br />
**[[4rzm]] – SlEH + lasalocid A<br />
**[[4rzm]] – SlEH + lasalocid A<br />
-
**[[5yb5]] – mbEH (mutant) + styrene derivative<br />
+
**[[6n3k]] – TrSEH + urea derivative inhibitor – ''Trichoderma reesei''<br />
 +
**[[6n3z]] – TrSEH + benzamide derivative inhibitor <br />
 +
**[[6n5h]] – TrSEH + benzoate derivative inhibitor <br />
 +
**[[6n5f]] – TrSEH + nonanamide derivative inhibitor <br />
 +
**[[6n5g]] – TrSEH + piperidine derivative inhibitor<br />
 +
**[[2zjf]] – MtSEH + inhibitor<br />
*Soluble epoxide hydrolase complex with inhibitor
*Soluble epoxide hydrolase complex with inhibitor
-
**[[1vj5]], [[1zd2]], [[1zd3]], [[1zd4]], [[1zd5]], [[3wk4]], [[4c4x]], [[4c4y]], [[4c4z]], [[5ai5]], [[5akz]], [[5ali]], [[6aum]], [[6fr2]] – hSEH + urea derivative inhibitor<br />
+
**[[1vj5]], [[1zd2]], [[1zd3]], [[1zd4]], [[1zd5]], [[3wk4]], [[4c4x]], [[4c4y]], [[4c4z]], [[5ai5]], [[5akz]], [[5ali]], [[6aum]], [[6fr2]], [[6hgx]] – hSEH + urea derivative inhibitor<br />
-
**[[1cr6]], [[1ek1]], [[1ek2]] – mSEH + urea derivative inhibitor<br />
+
**[[3otq]], [[3wk7]], [[4y2j]], [[4y2s]], [[4y2v]], [[5ak4]], [[5akh]], [[5aki]], [[5alk]], [[5alq]], [[5alv]], [[5aly]] – hSEH + pyrazole inhibitor<br />
**[[3otq]], [[3wk7]], [[4y2j]], [[4y2s]], [[4y2v]], [[5ak4]], [[5akh]], [[5aki]], [[5alk]], [[5alq]], [[5alv]], [[5aly]] – hSEH + pyrazole inhibitor<br />
**[[5akj]], [[5alf]], [[5als]] – hSEH + imidazole inhibitor<br />
**[[5akj]], [[5alf]], [[5als]] – hSEH + imidazole inhibitor<br />
Line 44: Line 53:
**[[3ans]], [[3ant]] – hSEH + synthetic inhibitor<br />
**[[3ans]], [[3ant]] – hSEH + synthetic inhibitor<br />
**[[3pdc]], [[5ale]] – hSEH catalytic domain + benzoxazole inhibitor<br />
**[[3pdc]], [[5ale]] – hSEH catalytic domain + benzoxazole inhibitor<br />
-
**[[4jnc]], [[5alx]] – hSEH catalytic domain + carboxamide inhibitor<br />
+
**[[4jnc]], [[5alx]], [[7p4k]] – hSEH catalytic domain + carboxamide inhibitor<br />
**[[4x6x]], [[4x6y]] – hSEH catalytic domain + cyclopropane inhibitor<br />
**[[4x6x]], [[4x6y]] – hSEH catalytic domain + cyclopropane inhibitor<br />
 +
**[[7a7g]] – hSEH catalytic domain + inhibitor<br />
**[[4hai]], [[3wka]], [[4ocz]], [[4od0]], [[5ake]], [[5alh]], [[5am1]] – hSEH + piperidine derivative inhibitor<br />
**[[4hai]], [[3wka]], [[4ocz]], [[4od0]], [[5ake]], [[5alh]], [[5am1]] – hSEH + piperidine derivative inhibitor<br />
**[[4y2p]], [[4y2q]], [[5ai4]], [[5ak5]], [[5ak6]], [[5alt]], [[5am5]] – hSEH + pyridine derivative inhibitor<br />
**[[4y2p]], [[4y2q]], [[5ai4]], [[5ak5]], [[5ak6]], [[5alt]], [[5am5]] – hSEH + pyridine derivative inhibitor<br />
**[[4y2r]] – hSEH + piperazine derivative inhibitor<br />
**[[4y2r]] – hSEH + piperazine derivative inhibitor<br />
**[[5akl]], [[5alm]], [[5am0]] – hSEH + pyrrolidine derivative inhibitor<br />
**[[5akl]], [[5alm]], [[5am0]] – hSEH + pyrrolidine derivative inhibitor<br />
 +
**[[6yl4]] – hSEH + benzamide derivative inhibitor <br />
**[[4y2t]], [[5aib]] – hSEH + benzyloxy derivative inhibitor<br />
**[[4y2t]], [[5aib]] – hSEH + benzyloxy derivative inhibitor<br />
**[[3wkb]] – hSEH + quinoxaline derivative inhibitor<br />
**[[3wkb]] – hSEH + quinoxaline derivative inhibitor<br />
Line 58: Line 69:
**[[3wke]], [[5am3]] – hSEH + carbamoyl derivative inhibitor<br />
**[[3wke]], [[5am3]] – hSEH + carbamoyl derivative inhibitor<br />
**[[4j03]] – hSEH + fulvestrant<br />
**[[4j03]] – hSEH + fulvestrant<br />
 +
**[[6hgv]] – hSEH + talinonol<br />
 +
**[[7eba]] – hSEH + kurarinone<br />
**[[5ai0]] – hSEH + phenyl oxadiazolamine inhibitor<br />
**[[5ai0]] – hSEH + phenyl oxadiazolamine inhibitor<br />
**[[5ai9]] – hSEH + phenol derivative inhibitor<br />
**[[5ai9]] – hSEH + phenol derivative inhibitor<br />
**[[5aia]], [[5mwa]] – hSEH + benzoate derivative inhibitor<br />
**[[5aia]], [[5mwa]] – hSEH + benzoate derivative inhibitor<br />
**[[5ak3]] – hSEH + indan-amine derivative inhibitor<br />
**[[5ak3]] – hSEH + indan-amine derivative inhibitor<br />
 +
**[[6hgw]] – hSEH + ethanamine derivative inhibitor<br />
**[[5all]] – hSEH + cyclohexyl methanol inhibitor<br />
**[[5all]] – hSEH + cyclohexyl methanol inhibitor<br />
**[[6i5g]] – hSEH C terminal + prostaglandin derivative<br />
**[[6i5g]] – hSEH C terminal + prostaglandin derivative<br />
 +
**[[1cr6]], [[1ek1]], [[1ek2]] – mSEH + urea derivative inhibitor<br />
**[[4o08]] – BmSEH + phenoxy acetamide inhibitor<br />
**[[4o08]] – BmSEH + phenoxy acetamide inhibitor<br />
Line 72: Line 87:
*Limonene-1,2-epoxide hydrolase
*Limonene-1,2-epoxide hydrolase
-
**[[1nww]] – ReEH – ''Rhodococcus erythropolis''<br />
+
**[[1nww]] – ReLEH – ''Rhodococcus erythropolis''<br />
-
**[[4r9k]], [[4r9l]], [[4xbx]], [[4xdw]], [[5cf1]], [[5cf2]], [[5jpp]], [[5gkw]] – ReEH (mutant)<br />
+
**[[4r9k]], [[4r9l]], [[4xbx]], [[4xdw]], [[5cf1]], [[5cf2]], [[5jpp]], [[5gkw]], [[7vwd]], [[7vwm]], [[7vx2]] – ReLEH (mutant)<br />
-
**[[1nu3]] – ReEH + valpromide <br />
+
**[[1nu3]] – ReLEH + valpromide <br />
-
**[[4xbt]], [[4xdv]], [[5clk]], [[5jpu]], [[5yao]] – ReEH (mutant) + hexane derivative<br />
+
**[[4xbt]], [[4xdv]], [[5clk]], [[5jpu]], [[5yao]] – ReLEH (mutant) + hexane derivative<br />
-
**[[4xby]], [[5ck6]], [[5yng]], [[5yqt]] – ReEH (mutant) + cyclopentene oxide<br />
+
**[[4xby]], [[5ck6]], [[5yng]], [[5yqt]] – ReLEH (mutant) + cyclopentene oxide<br />
-
**[[5aif]], [[5aih]], [[5aii]] – mlEH – metagenomic library<br />
+
**[[7xee]] – ReLEH (mutant) + ethanamide derivative<br />
-
**[[5aig]] – mlEH + valpromide <br />
+
**[[7xef]] – ReLEH (mutant) + pyrrolidine derivative<br />
 +
**[[5aif]], [[5aih]], [[5aii]] – mlLEH – metagenomic library<br />
 +
**[[5aig]] – mlLEH + valpromide <br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D Structures of epoxide hydrolase

Updated on 23-February-2023

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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