6pbz
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Escherichia coli GppA== | |
| - | + | <StructureSection load='6pbz' size='340' side='right'caption='[[6pbz]], [[Resolution|resolution]] 2.48Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6pbz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PBZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PBZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.475Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pbz OCA], [https://pdbe.org/6pbz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pbz RCSB], [https://www.ebi.ac.uk/pdbsum/6pbz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pbz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GPPA_ECOLI GPPA_ECOLI] Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities (PubMed:6130093, PubMed:8394006). In vitro, can hydrolyze pppGp (PubMed:6130093). Also has exopolyphosphatase activity, catalyzing the release of orthophosphate by processive hydrolysis of the phosphoanyhydride bonds of polyphosphate chains (1000 residues) (PubMed:8394006).<ref>PMID:6130093</ref> <ref>PMID:8394006</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ji X]] | ||
| + | [[Category: Shaw GX]] | ||
| + | [[Category: Song H]] | ||
| + | [[Category: Wang C]] | ||
Current revision
Crystal structure of Escherichia coli GppA
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