4znl

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<StructureSection load='4znl' size='340' side='right'caption='[[4znl]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
<StructureSection load='4znl' size='340' side='right'caption='[[4znl]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4znl]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_phage_p74-26 Thermus phage p74-26]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZNL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZNL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4znl]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_virus_P74-26 Thermus virus P74-26]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZNL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.068&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zni|4zni]], [[4znj|4znj]], [[4znk|4znk]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">P74p84 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=466052 Thermus phage P74-26])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4znl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4znl OCA], [https://pdbe.org/4znl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4znl RCSB], [https://www.ebi.ac.uk/pdbsum/4znl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4znl ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4znl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4znl OCA], [http://pdbe.org/4znl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4znl RCSB], [http://www.ebi.ac.uk/pdbsum/4znl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4znl ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A7XXR1_BP742 A7XXR1_BP742] The terminase large subunit acts as an ATP driven molecular motor necessary for viral DNA translocation into empty capsids and as an endonuclease that cuts the viral genome to initiate and to end a packaging reaction. The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit involved in viral DNA recognition (packaging sequence), and a large terminase subunit possessing endonucleolytic and ATPase activities. Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine. The terminase large subunit exhibits endonuclease activity and cleaves the viral genome concatemer. Once the capsid is packaged with the DNA, the terminase complex is substituted by the tail.[HAMAP-Rule:MF_04146]
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Terminase|Terminase]]
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*[[Terminase 3D Structures|Terminase 3D Structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Thermus phage p74-26]]
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[[Category: Thermus virus P74-26]]
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[[Category: Duffy, C M]]
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[[Category: Duffy CM]]
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[[Category: Hayes, J A]]
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[[Category: Hayes JA]]
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[[Category: Hilbert, B J]]
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[[Category: Hilbert BJ]]
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[[Category: Kelch, B A]]
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[[Category: Kelch BA]]
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[[Category: Stone, N P]]
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[[Category: Stone NP]]
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[[Category: Dna translocation]]
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[[Category: Viral protein]]
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Current revision

Thermus Phage P74-26 Large Terminase ATPase domain bound to ADP Beryllium Fluoride

PDB ID 4znl

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