5a28
From Proteopedia
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<StructureSection load='5a28' size='340' side='right'caption='[[5a28]], [[Resolution|resolution]] 1.48Å' scene=''> | <StructureSection load='5a28' size='340' side='right'caption='[[5a28]], [[Resolution|resolution]] 1.48Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5a28]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5a28]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A28 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene>, <scene name='pdbligand=TUQ:4-(4-CHLORO-2-{5-[(TRIMETHYL-1H-PYRAZOL-4-YL)METHYL]-1,3,4-OXADIAZOL-2-YL}PHENOXY)PIPERIDINE'>TUQ</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene>, <scene name='pdbligand=TUQ:4-(4-CHLORO-2-{5-[(TRIMETHYL-1H-PYRAZOL-4-YL)METHYL]-1,3,4-OXADIAZOL-2-YL}PHENOXY)PIPERIDINE'>TUQ</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a28 OCA], [https://pdbe.org/5a28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a28 RCSB], [https://www.ebi.ac.uk/pdbsum/5a28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a28 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/Q4Q5S8_LEIMA Q4Q5S8_LEIMA] Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins (By similarity). |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Glycylpeptide N-tetradecanoyltransferase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Leishmania major]] |
| - | [[Category: Barker | + | [[Category: Barker KV]] |
| - | [[Category: Brannigan | + | [[Category: Brannigan JA]] |
| - | [[Category: Heal | + | [[Category: Heal WP]] |
| - | [[Category: Leatherbarrow | + | [[Category: Leatherbarrow RJ]] |
| - | [[Category: Paape | + | [[Category: Paape D]] |
| - | [[Category: Rackham | + | [[Category: Rackham MD]] |
| - | [[Category: Smith | + | [[Category: Smith DF]] |
| - | [[Category: Tate | + | [[Category: Tate EW]] |
| - | [[Category: Wilkinson | + | [[Category: Wilkinson AJ]] |
| - | [[Category: Yu | + | [[Category: Yu Z]] |
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Current revision
Leishmania major N-myristoyltransferase in complex with a chlorophenyl 1,3,4-oxadiazole inhibitor.
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Categories: Large Structures | Leishmania major | Barker KV | Brannigan JA | Heal WP | Leatherbarrow RJ | Paape D | Rackham MD | Smith DF | Tate EW | Wilkinson AJ | Yu Z
