This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6pey
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6pey is ON HOLD Authors: Gallagher, E.L., Gurney, L.A., Frasco, F.G., Trimmer, E., Bolen, R.L., Collins, K., Garland, E., Halloran, J., Handley-Pend...) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==MTHFR with mutation Asp120Ala== | |
| + | <StructureSection load='6pey' size='340' side='right'caption='[[6pey]], [[Resolution|resolution]] 2.88Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6pey]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PEY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PEY FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.88Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pey OCA], [https://pdbe.org/6pey PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pey RCSB], [https://www.ebi.ac.uk/pdbsum/6pey PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pey ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/METF_ECOLI METF_ECOLI] Methylenetetrahydrofolate reductase required to generate the methyl groups necessary for methionine synthetase to convert homocysteine to methionine.<ref>PMID:14275142</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Methylenetetrahydrofolate reductase 3D structures|Methylenetetrahydrofolate reductase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Escherichia coli]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Bolen RL]] |
| - | [[Category: | + | [[Category: Collins K]] |
| - | [[Category: | + | [[Category: Frasco FG]] |
| - | [[Category: | + | [[Category: Gallagher EL]] |
| - | [[Category: Hernandez | + | [[Category: Garland E]] |
| - | [[Category: | + | [[Category: Gurney LA]] |
| - | [[Category: Soares | + | [[Category: Halloran J]] |
| - | [[Category: | + | [[Category: Handley-Pendelton J]] |
| - | [[Category: | + | [[Category: Hernandez V]] |
| - | [[Category: | + | [[Category: Leffler S]] |
| + | [[Category: Perez A]] | ||
| + | [[Category: Soares A]] | ||
| + | [[Category: Stojanoff V]] | ||
| + | [[Category: Trimmer E]] | ||
| + | [[Category: Williams D]] | ||
Current revision
MTHFR with mutation Asp120Ala
| |||||||||||
Categories: Escherichia coli | Large Structures | Bolen RL | Collins K | Frasco FG | Gallagher EL | Garland E | Gurney LA | Halloran J | Handley-Pendelton J | Hernandez V | Leffler S | Perez A | Soares A | Stojanoff V | Trimmer E | Williams D
