6pgv
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human Josephin-2 in complex with ubiquitin== | |
| + | <StructureSection load='6pgv' size='340' side='right'caption='[[6pgv]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6pgv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PGV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PGV FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NEH:ETHANAMINE'>NEH</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pgv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pgv OCA], [https://pdbe.org/6pgv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pgv RCSB], [https://www.ebi.ac.uk/pdbsum/6pgv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pgv ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/JOS2_HUMAN JOS2_HUMAN] Cleaves 'Lys-63'-linked poly-ubiquitin chains, and with lesser efficiency 'Lys-48'-linked poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme.<ref>PMID:17696782</ref> <ref>PMID:21118805</ref> <ref>PMID:23625928</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[3D structures of ubiquitin|3D structures of ubiquitin]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Grasty KC]] | ||
| + | [[Category: Loll PJ]] | ||
| + | [[Category: Weeks SD]] | ||
Current revision
Human Josephin-2 in complex with ubiquitin
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