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5aoy

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<StructureSection load='5aoy' size='340' side='right'caption='[[5aoy]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='5aoy' size='340' side='right'caption='[[5aoy]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5aoy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AOY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5aoy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AOY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AOY FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5aoy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aoy OCA], [http://pdbe.org/5aoy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5aoy RCSB], [http://www.ebi.ac.uk/pdbsum/5aoy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5aoy ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aoy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aoy OCA], [https://pdbe.org/5aoy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aoy RCSB], [https://www.ebi.ac.uk/pdbsum/5aoy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aoy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ENDOV_MOUSE ENDOV_MOUSE]] Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine. Has strong preference for single-stranded RNAs (ssRNAs) toward double-stranded RNAs (dsRNAs). Cleaves mRNAs and tRNAs containing inosine. Also able to cleave structure-specific dsRNA substrates containing the specific sites 5'-IIUI-3' and 5'-UIUU-3'. Inosine is present in a number of RNAs following editing; the function of inosine-specific endoribonuclease is still unclear: it could either play a regulatory role in edited RNAs, or be involved in antiviral response by removing the hyperedited long viral dsRNA genome that has undergone A-to-I editing. Binds branched DNA structures (By similarity).
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[https://www.uniprot.org/uniprot/ENDOV_MOUSE ENDOV_MOUSE] Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine. Has strong preference for single-stranded RNAs (ssRNAs) toward double-stranded RNAs (dsRNAs). Cleaves mRNAs and tRNAs containing inosine. Also able to cleave structure-specific dsRNA substrates containing the specific sites 5'-IIUI-3' and 5'-UIUU-3'. Inosine is present in a number of RNAs following editing; the function of inosine-specific endoribonuclease is still unclear: it could either play a regulatory role in edited RNAs, or be involved in antiviral response by removing the hyperedited long viral dsRNA genome that has undergone A-to-I editing. Binds branched DNA structures (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Alseth, I]]
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[[Category: Alseth I]]
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[[Category: Bjoras, M]]
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[[Category: Bjoras M]]
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[[Category: Dalhus, B]]
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[[Category: Dalhus B]]
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[[Category: Nawaz, M S]]
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[[Category: Nawaz MS]]
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[[Category: Ronander, M E]]
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[[Category: Ronander ME]]
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[[Category: Solvoll, A M]]
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[[Category: Solvoll AM]]
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[[Category: Strom-Andersen, P]]
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[[Category: Strom-Andersen P]]
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[[Category: Vik, E S]]
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[[Category: Vik ES]]
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[[Category: Endonuclease]]
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[[Category: Endonuclease v]]
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[[Category: Hydrolase]]
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Current revision

Structure of mouse Endonuclease V

PDB ID 5aoy

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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