1in0

<table><tr><td colspan='2'>[[1in0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IN0 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MMC:METHYL+MERCURY+ION'>MMC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1in0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1in0 OCA], [http://pdbe.org/1in0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1in0 RCSB], [http://www.ebi.ac.uk/pdbsum/1in0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1in0 ProSAT]</span></td></tr>

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== Publication Abstract from PubMed ==

A hypothetical protein encoded by the gene YajQ of Haemophilus influenzae was selected, as part of a structural genomics project, for X-ray crystallographic structure determination and analysis to assist with the functional assignment. The protein is present in most bacteria, but not in archaea or eukaryotes. The amino acid sequence has no homology to that of other proteins. The YajQ protein was cloned, expressed, and the crystal structure determined at 2.1-A resolution by applying the multiwavelength anomalous dispersion method to a mercury derivative. The polypeptide chain is folded into two domains with identical folding topology. Each domain has a four-stranded antiparallel beta-sheet flanked on one side by two alpha-helices. This structural motif is a characteristic feature of many RNA-binding proteins. The tetrameric structure observed in the crystal suggests a possibility of binding two stretches of double-stranded nucleic acid.

Crystal structure of the YajQ protein from Haemophilus influenzae reveals a tandem of RNP-like domains.,Teplyakov A, Obmolova G, Bir N, Reddy P, Howard AJ, Gilliland GL J Struct Funct Genomics. 2003;4(1):1-9. PMID:12943362<ref>PMID:12943362</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

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<div class="pdbe-citations 1in0" style="background-color:#fffaf0;"></div>

== References ==

<references/>

[[Category: Gilliland, G L]]

[[Category: S2F, Structure 2.Function Project]]

[[Category: Teplyakov, A]]

[[Category: Unknown function]]