Gcn4
From Proteopedia
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== Function == | == Function == | ||
| - | '''Gcn4''' is a yeast transcriptional activator. It belongs to a large family of eukaryotic transcription factors including Fos, Jun and CREB. <ref>PMID:7934812</ref> Gcn4-pLI is a 33-residue peptide of the dimerization domain of Gcn4. See also [[Intrinsically Disordered Protein]]. | + | '''Gcn4''' or '''General control protein Gcn4''' is a yeast transcriptional activator. It belongs to a large family of eukaryotic transcription factors including Fos, Jun and CREB. <ref>PMID:7934812</ref> Gcn4-pLI is a 33-residue peptide of the dimerization domain of Gcn4. See also [[Intrinsically Disordered Protein]]. |
== Structural highlights == | == Structural highlights == | ||
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== 3D Structures of Gcn4 == | == 3D Structures of Gcn4 == | ||
| - | [[ | + | [[Gcn4 3D Structures]] |
</StructureSection> | </StructureSection> | ||
| - | == 3D Structures of Gcn4 == | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *Gcn4 coiled-coil domain residues 250-281 | ||
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| - | **[[2zta]], [[1w5i]], [[2b1f]], [[2b22]], [[2ag3]], [[2r2v]], [[4c46]], [[4hu5]], [[4hu6]] – yGcn4 - yeast <br /> | ||
| - | **[[2ovn]], [[2l56]], [[5iir]], [[5iiv]], [[5iew]] – yGcn4 - NMR<br /> | ||
| - | **[[3ck4]], [[3crp]], [[2ipz]] – yGcn4 tetramer <br /> | ||
| - | **[[1gcl]], [[1swi]], [[1ce9]], [[1w5g]], [[1w5h]], [[1w5j]], [[1w5k]], [[1w5l]], [[1unt]], [[1unu]], [[1unv]], [[1unw]], [[1unx]], [[1uny]], [[1unz]], [[1uo0]], [[1uo1]], [[1uo2]], [[1uo3]], [[1uo4]], [[1uo5]], [[1u9f]], [[1u9g]], [[1u9h]], [[2bni]], [[2cce]], [[2ccf]], [[2ccn]], [[2ahp]], [[2hy6]], [[3i1g]], [[2wpy]], [[2wpz]], [[2wq0]], [[2wq1]], [[2wq2]], [[2wq3]], [[3k7z]], [[3gjp]], [[3m48]], [[4niz]], [[4nj0]], [[4nj1]], [[4nj2]], [[4tl1]], [[5apq]], [[5aps]], [[5apt]], [[5apu]], [[5apv]], [[5apw]], [[5apx]], [[5apy]], [[6o2e]], [[6o2f]] – yGcn4 (mutant)<br /> | ||
| - | **[[1zii]], [[1zik]], [[1zil]] – yGcn4 dimer (mutant)<br /> | ||
| - | **[[2o7h]], [[1gcm]], [[1zij]], [[1zim]], [[1piq]], [[1ij0]], [[1ij1]], [[1ij2]], [[1ij3]], [[1rb4]], [[1rb5]], [[1rb6]] – yGcn4 trimer (mutant)<br /> | ||
| - | **[[2nrn]] – yGcn4 tetramer (mutant)<br /> | ||
| - | **[[1fmh]] – yGcn4 dimer (mutant) - NMR<br /> | ||
| - | **[[1ysa]], [[1dgc]], [[2dgc]] – yGcn4 dimer + DNA <br /> | ||
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| - | *Gcn4-pLI | ||
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| - | **[[2ag3]], [[2oxj]], [[2oxk]] – yGcn4-pLI (br /> | ||
| - | **[[1u2u]] – yGcn4-pLI dimer - NMR<br /> | ||
| - | **[[4dmd]], [[1kd8]], [[1kd9]], [[1kdd]] – yGcn4-pLI dimer <br /> | ||
| - | **[[4dme]] – yGcn4-pLI trimer <br /> | ||
| - | **[[1c94]] – yGcn4-pLI retro<br /> | ||
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| - | *Gcn4 transcription activation domain residues 101-134 | ||
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| - | **[[2lpb]] – yGcn4 + mediator of RNA polymerase II<br /> | ||
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| - | *Gcn4 fusion proteins | ||
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| - | **[[1gk6]] – yGcn4/vimentin<br /> | ||
| - | **[[2wg5]] – yGcn4/proteasome-activating nucleotidase<br /> | ||
| - | **[[2wg6]] – yGcn4 (mutant)/proteasome-activating nucleotidase<br /> | ||
| - | **[[2yny]], [[2ynz]], [[2yo0]], [[2yo1]], [[2yo2]], [[2yo3]], [[3zmf]] – yGcn4/inner membrane protein<br /> | ||
| - | **[[5app]] – yGcn4/outer membrane protein 100<br /> | ||
| - | **[[5apz]] – yGcn4/NOR1<br /> | ||
| - | **[[3i5c]] – yGcn4/WSPR response regulator<br /> | ||
| - | **[[3p8m]] – yGcn4/dynein<br /> | ||
| - | **[[4g2k]], [[1env]], [[1fav]], [[1gcl]], [[2q5u]], [[2q7c]], [[3g9r]] – yGcn4/virus envelope glycoprotein<br /> | ||
| - | **[[1kql]], [[2z5i]] – yGcn4/α-tropomyosin<br /> | ||
| - | **[[2z5h]] – yGcn4/α-tropomyosin + troponin T<br /> | ||
| - | **[[3bas]], [[3bat]] – yGcn4/myosin<br /> | ||
| - | **[[1wvl]], [[2d3e]], [[2efr]], [[2efs]], [[2g9j]] – yGcn4/SAC7D + DNA<br /> | ||
| - | **[[4m8m]] – yGcn4/plexin<br /> | ||
| - | **[[6hn4]], [[6hn5]] – yGcn4/insulin receptor<br /> | ||
| - | **[[6h9m]] – yGcn4/protein 90b<br /> | ||
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| - | *Gcn4 complex with protein | ||
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| - | **[[1ld4]] – yGcn4 + virus coat protein + virus spike glycoprotein<br /> | ||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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References
- ↑ Hinnebusch AG. Gene-specific translational control of the yeast GCN4 gene by phosphorylation of eukaryotic initiation factor 2. Mol Microbiol. 1993 Oct;10(2):215-23. PMID:7934812
