This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6pjj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "6pjj" [edit=sysop:move=sysop])
Current revision (07:30, 11 October 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 6pjj is ON HOLD
+
==Human PRPF4B bound to benzothiophene inhibitor 224==
-
 
+
<StructureSection load='6pjj' size='340' side='right'caption='[[6pjj]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
Authors: Godoi, P.H.C., Santiago, A.S., Fala, A.M., Ramos, P.Z., Sriranganadane, D., Mascarello, A., Segretti, N., Azevedo, H., Guimaraes, C.R.W., Arruda, P., Elkins, J.M., Counago, R.M., Structural Genomics Consortium (SGC)
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[6pjj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PJJ FirstGlance]. <br>
-
Description: Human PRPF4B bound to benzothiophene inhibitor 224
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OCJ:4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide'>OCJ</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
-
[[Category: Fala, A.M]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pjj OCA], [https://pdbe.org/6pjj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pjj RCSB], [https://www.ebi.ac.uk/pdbsum/6pjj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pjj ProSAT]</span></td></tr>
-
[[Category: Elkins, J.M]]
+
</table>
-
[[Category: Guimaraes, C.R.W]]
+
== Function ==
-
[[Category: Segretti, N]]
+
[https://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.
-
[[Category: Arruda, P]]
+
__TOC__
-
[[Category: Structural Genomics Consortium (Sgc)]]
+
</StructureSection>
-
[[Category: Santiago, A.S]]
+
[[Category: Homo sapiens]]
-
[[Category: Sriranganadane, D]]
+
[[Category: Large Structures]]
-
[[Category: Azevedo, H]]
+
[[Category: Arruda P]]
-
[[Category: Mascarello, A]]
+
[[Category: Azevedo H]]
-
[[Category: Counago, R.M]]
+
[[Category: Counago RM]]
-
[[Category: Ramos, P.Z]]
+
[[Category: Elkins JM]]
-
[[Category: Godoi, P.H.C]]
+
[[Category: Fala AM]]
 +
[[Category: Godoi PHC]]
 +
[[Category: Guimaraes CRW]]
 +
[[Category: Mascarello A]]
 +
[[Category: Ramos PZ]]
 +
[[Category: Santiago AS]]
 +
[[Category: Segretti N]]
 +
[[Category: Sriranganadane D]]

Current revision

Human PRPF4B bound to benzothiophene inhibitor 224

PDB ID 6pjj

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools