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6pk6

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'''Unreleased structure'''
 
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The entry 6pk6 is ON HOLD
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==Human PRPF4B bound to benzothiophene inhibitor 329==
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<StructureSection load='6pk6' size='340' side='right'caption='[[6pk6]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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Authors: Godoi, P.H.C., Santiago, A.S., Fala, A.M., Ramos, P.Z., Sriranganadane, D., Mascarello, A., Segretti, N., Azevedo, H., Guimaraes, C.R.W., Arruda, P., Elkins, J.M., Counago, R.M., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6pk6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PK6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PK6 FirstGlance]. <br>
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Description: Human PRPF4B bound to benzothiophene inhibitor 329
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OND:4-(5-{[(2-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide'>OND</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Fala, A.M]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pk6 OCA], [https://pdbe.org/6pk6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pk6 RCSB], [https://www.ebi.ac.uk/pdbsum/6pk6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pk6 ProSAT]</span></td></tr>
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[[Category: Elkins, J.M]]
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</table>
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[[Category: Guimaraes, C.R.W]]
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== Function ==
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[[Category: Segretti, N]]
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[https://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.
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[[Category: Arruda, P]]
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__TOC__
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[[Category: Structural Genomics Consortium (Sgc)]]
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</StructureSection>
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[[Category: Santiago, A.S]]
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[[Category: Homo sapiens]]
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[[Category: Sriranganadane, D]]
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[[Category: Large Structures]]
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[[Category: Azevedo, H]]
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[[Category: Arruda P]]
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[[Category: Mascarello, A]]
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[[Category: Azevedo H]]
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[[Category: Counago, R.M]]
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[[Category: Counago RM]]
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[[Category: Ramos, P.Z]]
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[[Category: Elkins JM]]
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[[Category: Godoi, P.H.C]]
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[[Category: Fala AM]]
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[[Category: Godoi PHC]]
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[[Category: Guimaraes CRW]]
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[[Category: Mascarello A]]
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[[Category: Ramos PZ]]
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[[Category: Santiago AS]]
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[[Category: Segretti N]]
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[[Category: Sriranganadane D]]

Current revision

Human PRPF4B bound to benzothiophene inhibitor 329

PDB ID 6pk6

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