6pkw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "6pkw" [edit=sysop:move=sysop])
Current revision (09:26, 20 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 6pkw is ON HOLD
+
==Cryo-EM structure of the zebrafish TRPM2 channel in the apo conformation, processed with C2 symmetry (pseudo C4 symmetry)==
-
 
+
<SX load='6pkw' size='340' side='right' viewer='molstar' caption='[[6pkw]], [[Resolution|resolution]] 4.50&Aring;' scene=''>
-
Authors:
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[6pkw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PKW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PKW FirstGlance]. <br>
-
Description:
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.5&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pkw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pkw OCA], [https://pdbe.org/6pkw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pkw RCSB], [https://www.ebi.ac.uk/pdbsum/6pkw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pkw ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TRPM2_DANRE TRPM2_DANRE] Nonselective, voltage-independent cation channel that mediates Ca(2+) influx, leading to increased cytoplasmic Ca(2+) levels. Functions as ligand-gated ion channel. Binding of ADP-ribose to the cytoplasmic N-terminal region causes a conformation change; the channel is primed but still requires Ca(2+) binding to trigger channel opening.<ref>PMID:30250252</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</SX>
 +
[[Category: Danio rerio]]
 +
[[Category: Large Structures]]
 +
[[Category: Borgnia MJ]]
 +
[[Category: Borschel WF]]
 +
[[Category: Hsu AL]]
 +
[[Category: Lander GC]]
 +
[[Category: Lee S-Y]]
 +
[[Category: Wu M]]
 +
[[Category: Yin Y]]

Current revision

Cryo-EM structure of the zebrafish TRPM2 channel in the apo conformation, processed with C2 symmetry (pseudo C4 symmetry)

6pkw, resolution 4.50Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6pkw"
Personal tools