6ig2

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<StructureSection load='6ig2' size='340' side='right'caption='[[6ig2]], [[Resolution|resolution]] 2.88&Aring;' scene=''>
<StructureSection load='6ig2' size='340' side='right'caption='[[6ig2]], [[Resolution|resolution]] 2.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6ig2]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IG2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6ig2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IG2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.882&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidate_cytidylyltransferase Phosphatidate cytidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.41 2.7.7.41] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ig2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ig2 OCA], [http://pdbe.org/6ig2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ig2 RCSB], [http://www.ebi.ac.uk/pdbsum/6ig2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ig2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ig2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ig2 OCA], [https://pdbe.org/6ig2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ig2 RCSB], [https://www.ebi.ac.uk/pdbsum/6ig2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ig2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TAM41_SCHPO TAM41_SCHPO]] Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.[UniProtKB:P53230]
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[https://www.uniprot.org/uniprot/TAM41_SCHPO TAM41_SCHPO] Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.[UniProtKB:P53230]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Phosphatidate cytidylyltransferase]]
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[[Category: Schizosaccharomyces pombe 972h-]]
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[[Category: Jiao, H Z]]
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[[Category: Jiao HZ]]
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[[Category: Liu, Z F]]
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[[Category: Liu ZF]]
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[[Category: Yin, Y]]
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[[Category: Yin Y]]
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[[Category: Cdp-diacylglycerol synthase]]
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[[Category: Mitochondrial inner membrane]]
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[[Category: Ntase fold]]
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[[Category: Transferase]]
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Current revision

Structure of mitochondrial CDP-DAG synthase Tam41 complexed with CTP, delta 74, F240A

PDB ID 6ig2

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