6k28

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<StructureSection load='6k28' size='340' side='right'caption='[[6k28]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='6k28' size='340' side='right'caption='[[6k28]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6k28]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K28 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6K28 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6k28]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6K28 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TZE:2-(4-METHYL-THIAZOL-5-YL)-ETHANOL'>TZE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.002&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.50 2.7.1.50] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TZE:2-(4-METHYL-THIAZOL-5-YL)-ETHANOL'>TZE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6k28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k28 OCA], [http://pdbe.org/6k28 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6k28 RCSB], [http://www.ebi.ac.uk/pdbsum/6k28 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6k28 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6k28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k28 OCA], [https://pdbe.org/6k28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6k28 RCSB], [https://www.ebi.ac.uk/pdbsum/6k28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6k28 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/W9BB97_KLEPN W9BB97_KLEPN]] Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).[HAMAP-Rule:MF_00228][SAAS:SAAS00158945]
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[https://www.uniprot.org/uniprot/W9BB97_KLEPN W9BB97_KLEPN] Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).[HAMAP-Rule:MF_00228][SAAS:SAAS00158945]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Transferase]]
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[[Category: Chen Y]]
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[[Category: Chen, Y]]
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[[Category: Lan J]]
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[[Category: Lan, J]]
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[[Category: Liu W]]
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[[Category: Liu, W]]
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[[Category: Shang F]]
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[[Category: Shang, F]]
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[[Category: Wang L]]
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[[Category: Wang, L]]
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[[Category: Xu Y]]
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[[Category: Xu, Y]]
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[[Category: Klebsiella pneumonia]]
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[[Category: Thim]]
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Current revision

Crystal structure of the 5-(Hydroxyethyl)-methylthiazole Kinase ThiM from Klebsiella pneumonia in complex with TZE

PDB ID 6k28

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