Glycosyltransferase

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Cyclodextrin glycosyltransferase complex with substrate maltoheptaose, maltose and Ca+2 ions, 1cxh

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References

↑ Williams GJ, Thorson JS. Natural product glycosyltransferases: properties and applications. Adv Enzymol Relat Areas Mol Biol. 2009;76:55-119. PMID:18990828
↑ Qasba PK, Ramakrishnan B, Boeggeman E. Structure and function of beta -1,4-galactosyltransferase. Curr Drug Targets. 2008 Apr;9(4):292-309. PMID:18393823
↑ Lin Y, Sun X, Hou X, Qu B, Gao X, Li Q. Effects of glucose on lactose synthesis in mammary epithelial cells from dairy cow. BMC Vet Res. 2016 May 26;12:81. PMID:27229304 doi:10.1186/s12917-016-0704-x
↑ Jadhav SK, Patel KA, Dholakia BB, Khan BM. Structural characterization of a flavonoid glycosyltransferase from Withania somnifera. Bioinformation. 2012;8(19):943-9. doi: 10.6026/97320630008943. Epub 2012 Oct 1. PMID:23144555 doi:http://dx.doi.org/10.6026/97320630008943
↑ Uitdehaag JC, Kalk KH, van Der Veen BA, Dijkhuizen L, Dijkstra BW. The cyclization mechanism of cyclodextrin glycosyltransferase (CGTase) as revealed by a gamma-cyclodextrin-CGTase complex at 1.8-A resolution. J Biol Chem. 1999 Dec 3;274(49):34868-76. PMID:10574960
↑ Lethe MCL, Paris V, Wang X, Chan CTY. Similarities in Structure and Function of UDP-Glycosyltransferase Homologs from Human and Plants. Int J Mol Sci. 2024 Feb 28;25(5):2782. PMID:38474028 doi:10.3390/ijms25052782
↑ Liu MZ, Wang D, Li Y, Li X, Zong G, Fei S, Yang X, Lin J, Wang X, Shen Y. Crystal Structures of C-glucosyltransferase UGT708C1 Provide Insights into the Mechanism of C-glycosylation. Plant Cell. 2020 Jul 22. pii: tpc.20.00002. doi: 10.1105/tpc.20.00002. PMID:32699169 doi:http://dx.doi.org/10.1105/tpc.20.00002
↑ Wang TS, Manning SA, Walker S, Kahne D. Isolated peptidoglycan glycosyltransferases from different organisms produce different glycan chain lengths. J Am Chem Soc. 2008 Oct 29;130(43):14068-9. PMID:18834124 doi:10.1021/ja806016y
↑ Abuelizz HA, Mahmud T. Distinct Substrate Specificity and Catalytic Activity of the Pseudoglycosyltransferase VldE. Chem Biol. 2015 Jun 18;22(6):724-33. PMID:26051218 doi:10.1016/j.chembiol.2015.04.021
↑ Yoshida A, Kobayashi K, Manya H, Taniguchi K, Kano H, Mizuno M, Inazu T, Mitsuhashi H, Takahashi S, Takeuchi M, Herrmann R, Straub V, Talim B, Voit T, Topaloglu H, Toda T, Endo T. Muscular dystrophy and neuronal migration disorder caused by mutations in a glycosyltransferase, POMGnT1. Dev Cell. 2001 Nov;1(5):717-24. PMID:11709191
↑ Knegtel RM, Strokopytov B, Penninga D, Faber OG, Rozeboom HJ, Kalk KH, Dijkhuizen L, Dijkstra BW. Crystallographic studies of the interaction of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 with natural substrates and products. J Biol Chem. 1995 Dec 8;270(49):29256-64. PMID:7493956

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Glycosyltransferase

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3D structures of glycosyltransferase

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 == Function ==
-'''Glycosyltransferase''' (GT) are enzymes which catalyze the transfer of monosaccharide to alcohol, carbohydrate, protein or inorganic phosphate<ref>PMID:18990828</ref>. <br />
+*'''Glycosyltransferase''' (GT) are enzymes which catalyze the transfer of monosaccharide to alcohol, carbohydrate, protein or inorganic phosphate<ref>PMID:18990828</ref>. <br />
-'''Galactosyltransferase''' (AGT) is a GT which catalyzes  the transfer of galactose during the synthesis of polysaccharides<ref>PMID:18393823</ref>.<br />
+*'''Galactosyltransferase''' (AGT) is a GT which catalyzes  the transfer of galactose during the synthesis of polysaccharides<ref>PMID:18393823</ref>.<br />
-'''Fucosylglycoprotein 3-AGT''' (GTB) or '''histo-blood group ABO system transferase''' is the basis of the blood ABO system.  It involves 3 carbohydrate antigens: A, B and H. <br />
+*'''Beta-1,4-galactosyltransferase''' (BGT) is the catalytic subunit of lactose synthase of which [[Alpha-lactalbumin]] is the regulatory  subunit.  Lactose synthase synthesises lactose from UDP-galactose and glucose<ref>PMID:27229304</ref>.  See [[Human Lactose synthase(Hebrew)]].<br />
-'''Flavonoid GT''' glycosylates flavonoids (plant metabolites with two phenyl rings and one heterocyclic ring)<ref>PMID:23144555</ref>.  For details on flavonoid GT see [[Vitis vinifera Flavonoid 3-O-Glucosyltransferase (Vv3GT)]].
+*'''Fucosylglycoprotein 3-AGT''' (GTB) or '''histo-blood group ABO system transferase''' is the basis of the blood ABO system.  It involves 3 carbohydrate antigens: A, B and H. <br />
+*'''Flavonoid GT''' glycosylates flavonoids (plant metabolites with two phenyl rings and one heterocyclic ring)<ref>PMID:23144555</ref>.  For details on flavonoid GT see [[Vitis vinifera Flavonoid 3-O-Glucosyltransferase (Vv3GT)]].
+*'''Cyclodextrin GT''' produces cyclodextrin from starch<ref>PMID:10574960</ref>.
+*'''UDP GT''' has a role in xenobiotics metabolism and metabolic waste<ref>PMID:38474028</ref>.
+*'''C-GT''' catalyzes the formation of C-glycosidic bonds<ref>PMID:32699169</ref>.
+*'''peptidoglycan GT''' synthesises the glycol strands of the bacterial walls' peptidoglycans <ref>PMID:18834124</ref>.
+*'''Pseudo-GT VldE''' catalyzes the condensation of 2 pseudo sugars to a product with an alpha, alpha-N-glycosidic bond<ref>PMID:26051218</ref>.
 == Relevance ==
@@ Line 20: / Line 26: @@
 </StructureSection>
-==3D structures of glycosyltransferase==
-Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-{{#tree:id=OrganizedByTopic|openlevels=0|
-*Cyclodextrin GT (CGT)
-**[[1cxi]], [[1cdg]], [[1cgt]], [[1cgu]] - BcCGT  – ''Bacillus circulans''
-**[[1tcm]], [[4cgt]], [[7cgt]], [[1kck]], [[1kcl]], [[1ot1]], [[1ot2]], [[1pez]], [[1pj9]], [[1v3j]], [[1v3k]], [[1cgv]], [[1cgw]] - BcCGT  (mutant)
-**[[1ciu]] – TtCGT – ''Thermoanaerobacterium thermosulfurigenes''
-**[[3bmv]], [[3bmw]] – TtCGT (mutant)<br />
-**[[1cyg]] – CGT – ''Geobacillus stearothermophilus''<br />
-**[[1d7f]] - BaCGT (mutant) – ''Bacillus''<br />
-**[[1pam]] - BaCGT<br />
-**[[4jcl]] - PmCGT – ''Paenibacillus macerans''<br />
-**[[6aij]] - PmCGT (mutant) <br />
-*''CGT binary complexes''
-**[[1cxe]], [[1cxh]] – BcCGT  + substrate
-**[[1cxf]], [[5cgt]], [[8cgt]], [[9cgt]], [[1cxk]], [[1eo5]], [[1eo7]] - BcCGT  (mutant) + substrate
-**[[3cgt]] - BcCGT  (mutant) + β-cyclodextrin
-**[[1d3c]] - BcCGT  (mutant) + γ-cyclodextrin
-**[[6cgt]] - BcCGT  (mutant) + HOXA
-**[[2dij]], [[1dtu]] - BcCGT  (mutant) + inhibitor
-**[[1cxl]] - BcCGT  (mutant) + reaction intermediate
-**[[2cxg]], [[1ukq]] – BcCGT + acarbose-derivative
-**[[1uks]], [[1ukt]], [[1v3l]], [[1v3m]] – BcCGT (mutant)  + acarbose-derivative<br />
-**[[1ded]] - BaCGT (mutant)  + acarbose<br />
-**[[1i75]] – BaCGT + deoxyjirimycin<br />
-**[[1a47]] – TtCGT + inhibitor
-*Maltose GT
-**[[1gju]], [[1lwh]] – TmMCG – ''Thermotoga maritima''
-**[[1gjw]] – TmMCG + maltose
-**[[1lwj]] - TmMGT + acarbose
-*Human GT
-**[[1lz0]] – hGT A - hGT A catalytic domain + inhibitor
-**[[1r7y]], [[1r81]] - hGT A catalytic domain + inhibitor + UDP-derivative
-**[[1lz7]] – hGT B catalytic domain
-**[[1r7u]], [[1r7x]] - hGT B catalytic domain + inhibitor
-**[[1r80]], [[1r82]] - hGT B catalytic domain + inhibitor + UDP-derivative
-**[[1lzi]] – hGT A catalytic domain + UDP + H antigen acceptor
-**[[1lzj]] – hGT B catalytic domain + UDP + H antigen acceptor
-**[[1r7t]], [[1r7v]] - hGT ABO(H) + inhibitor
-**[[1wt0]], [[1wsz]], [[1wt3]], [[2o1f]], [[2o1g]], [[3i0c]], [[3i0h]], [[1xz6]], [[2i7b]] – hGT ABO(H) (mutant)
-**[[1wt1]], [[1wt2]], [[2o1h]], [[3i0d]], [[3i0i]], [[2y7a]] - hGT ABO(H) (mutant) + UDP
-**[[3i0e]], [[3i0j]] - hGT ABO(H) (mutant) + H-antigen
-**[[3i0f]], [[3i0k]] - hGT ABO(H) (mutant) + H-antigen + UDP
-**[[3i0g]], [[3i0l]] - hGT ABO(H) (mutant) + DA + UDP-Gal
-*Oleandomycin GT
-**[[2iya]], [[2iyf]], [[4m60]], [[4m7p]] – SaGT – ''Strepromyces antibioticus''<br />
-**[[4m83]] – SaGT + UDP + erythromycin<br />
-*Hydroquinone GT
-**[[2vce]] – AtGT – ''Arabidopsis thaliana''<br />
-**[[2vch]], [[2vg8]] – AtGT + UDP
-*UDP GT
-**[[5tme]], [[5tmb]] – rGT OS 79 + UDP - rice <br />
-**[[6bk0]], [[6bk1]], [[6bk2]] - rGT OS 79 (mutant) + UDP <br />
-**[[5tmd]], [[6bk3]] – rGT OS 79 + UDP derivative + trichothecene<br />
-**[[5xvm]] - yGT 51 – yeast<br />
-**[[5gl5]] - yGT 51 + UDP-glucose <br />
-**[[5v2j]], [[5v2k]], [[5u6s]] – AtGT + UDP + laminaribiose + Br-benzoate<br />
-**[[5u6n]], [[5u6m]] – AtGT + UDP + laminaribiose + salicilate<br />
-**[[6o86]], [[6o87]] – SrGT + UDP – ''Stevia rebaudiana''<br />
-**[[6o88]] – SrGT + UDP + revaudioside<br />
-*C-GT
-**[[6jtd]] – GT + UDP – Trollius chinensis<br />
-*Flavonoid GT
-**[[3hbf]] – MtGT + UDP + myricetin – ''Medicago truncatula''
-**[[3hbj]] - MtGT + UDP
-**[[2pq6]] - MtGT
-**[[2c1x]], [[2c1z]] – GT + UDP – ''Vitis vinifera''
-*Peptidoglycan GT
-**[[4jbf]], [[4ovd]] – ApGT – ''Atopobium parvulum''<br />
-**[[4mnr]] – GT D,D transpeptidase domain – ''Eggerthella lenta''<br />
-**[[4n1x]], [[4qjg]], [[4r1g]], [[4r23]], [[4r3j]], [[4ra7]] – ApGT penicillin-binding domain + penicillin<br />
-**[[4qjg]], [[4r0q]] – ApGT penicillin-binding domain + antibiotic<br />
-**[[5uy7]] – GT – ''Burkholderia ambifaria''<br />
-**[[6bar]] – TtGT RODA – ''Thermus thermophilus''<br />
-**[[6bas]] – TtGT RODA (mutant) <br />
-**[[3hzs]], [[3vmq]], [[5zzk]] – SaGT - ''Staphylococcus aureus''<br />
-**[[6ftb]] – SaGT + moenomycin <br />
-*Various GT
-**[[2iuy]], [[2iv3]] – SvGT – ''Stretptomyces  viridochromogenes''
-**[[2jjm]] - BaGT – ''Bacillus anthracis''<br />
-**[[3oy2]] – PcvGT – ''Paramecium chiorela virus''<br />
-**[[3pnn]] – GT – ''Porphyromonas gingivalis''
-**[[2q3e]], [[3q3i]], [[3q3e]] – ApGT – ''Actinobacillus pleuropneumomiae''
-**[[1iir]] – AoUDP-GT – ''Amycolatopsis orientalis''
-**[[3h4i]], [[3h4t]] – GT chimera
-**[[1cwy]] – GT – ''Thermus aquaticus''
-**[[2iv7]], [[2iw1]], [[4rap]] – EcGT  - ''Escherichia coli''<br />
-**[[4xyw]] – EcGT (mutant) <br />
-**[[2xci]] – AaGT – ''Aquifex aeolicus''
-**[[3ia7]] – MeGT Calg4 – ''Micromonospora echinospora''
-**[[3otk]] – GT catalytic domain - mouse<br />
-**[[4ayl]] - BoGT – ''Bacterioides ovatus''<br />
-**[[4an4]], [[4amb]], [[4amg]] – GT Snogd – ''Streptomyces nogalater''<br />
-**[[3wad]] – ShGT – ''Streptomyces halstedii''<br />
-**[[4pqg]] – GT- ''Streptococcus pneumoniae''<br />
-**[[5du2]] - GT – ''Actinomadura verrucosospora''<br />
-**[[5a01]] – DmO-GT catalytic domain (mutant) – ''Drosophila melanogaster''<br />
-**[[6p61]] – GT – ''Leptospira borgpetersenii''<br />
-*Various GT complexes
-**[[1nzd]] – T4β-GT + UDP-glucose – Phage T4
-**[[2nzf]], [[1nzf]] - T4β-GT (mutant) + UDP-glucose<br />
-**[[3vmr]], [[3vms]], [[3vmt]] – SaGT + lipid II analog<br />
-**[[3mbo]] – BaGT + UDP + malate <br />
-**[[3oy7]] – PcvGT + GDP-mannose <br />
-**[[3q3h]] – ApGT + UDP-Glc<br />
-**[[1pn3]], [[1pnv]], [[1rrv]] – AoGT + TDP + vancomycin<br />
-**[[4rb4]] – EcGT (mutant) + ADP-heptose<br />
-**[[2yjn]] – GT + Dtpd-4-keto-6-deoxy-hexose isomerase – ''Saccharopolyspora erythraea''<br />
-**[[2xcu]] – AaGT + CMP<br />
-**[[3iaa]] – MeGT Calg2 + TDP
-**[[3rsc]] - MeGT Calg2 + TDP + calicheamicin<br />
-**[[4ayj]] – BoGT + glucose + galactose + fucose <br />
-**[[4cj8]], [[4cjc]] - BoGT (mutant) + UDP + galactosamine + UDP-galactosamine  <br />
-**[[4cjb]] - BoGT (mutant) + GalNac <br />
-**[[1g9r]] - GT (mutant) + UDP-galactose + Mn – ''Neisseria meningitides''<br />
-**[[3wag]] – ShGT + DTDP<br />
-**[[5ekp]] - SyGT + UDP – ''Synechosystis''<br />
-**[[5eke]] - SyGT (mutant) + UDP <br />
-**[[5e9u]], [[5e9t]] - GT + UDP + GlcNac + GT chaperone – ''Streptococcus gordonii''<br />
-**[[6ejj]] - CjGT + nerylneryl pyrophosphate + UDP  - ''Campylobacter jejuni''<br />
-**[[6eji]] - CjGT + UDP-galactosamine  <br />
-**[[6ejk]] - CjGT + nerylneryl pyrophosphate + UDP-galactosamine  <br />
-**[[5v4a]] - GT + UDP – ''Streptococcus sanguinis''<br />
-*β-1,4-galactosyltransferase 1 (BGT)
-**[[6fwu]], [[6fwt]] - hBGT 1 catalytic domain<br />
-**[[2fy7]] - hBGT 1 catalytic domain (mutant) <br />
-**[[1fgx]] - bBGT 1 catalytic domain – bovine<br />
-**[[1pzt]], [[4krv]] - bBGT 1 catalytic domain (mutant) <br />
-**[[3lw6]] - DmBGT 7 catalytic domain (mutant)
-*''BGT 1 binary complexes''
-**[[1oqm]] - bBGT catalytic domain + UDP-N-acetylgalactosamine<br />
-**[[2fya]] - hBGT 1 catalytic domain (mutant) + Mn<br />
-**[[4ee3]], [[4ee4]], [[4ee5]], [[4eea]], [[4eeg]], [[4eem]], [[4eeo]] - hBGT 1 catalytic domain (mutant) + polysaccharide<br />
-**[[1fr8]], [[1o0r]] - bBGT 1 catalytic domain + UDP-galactose<br />
-**[[1tw5]] - bBGT catalytic domain (mutant) + chitobiose<br />
-**[[1nf5]] - bBGT + α-lactalbumin<br />
-**[[4l41]] - bBGT 1 (mutant) + α-lactalbumin<br />
-**[[1o23]] - bBGT catalytic domain + UDP-glucose<br />
-**[[1oqm]] - bBGT catalytic domain + UDP-N-acetylgalactosamine<br />
-*''BGT 1 ternary complexes''
-**[[2fyb]] - hBGT 1 catalytic domain (mutant) + Mn + UDP<br />
-**[[2ae7]]-  hBGT 1 catalytic domain + UDP + pentasaccharide<br />
-**[[2aec]], [[2aes]], [[2agd]] - hBGT 1 catalytic domain + UDP + GlcNAc + mannose<br />
-**[[2fyc]] - hBGT 1 catalytic domain (mutant) + UDP-galactose + Ca + α-lactalbumin<br />
-**[[3ee5]] - hBGT 1 catalytic domain (mutant) + UDP + GlcNAc-β1,3-gal-β-naphthalenemethanol<br />
-**[[2fyd]] - hBGT 1 catalytic domain + UDP-GlcNAc + Mn + α-lactalbumin<br /> (mutant) + glucose<br />
-**[[2ah9]] - hBGT 1 catalytic domain + UDP + chitotriose<br />
-**[[1nhe]], [[1nkh]] - bBGT 1 catalytic domain + UDP + α-lactalbumin<br />
-**[[1yro]] - bBGT 1 catalytic domain (mutant) + UDP-galactose + α-lactalbumin<br />
-**[[1nwg]] - bBGT catalytic domain + N-butanoyl-glucoamine + α-lactalbumin<br />
-**[[1nmm]], [[1nqi]], [[1pzy]], [[1o7q]] - bBGT 1 catalytic domain + UDP + GlcNAc<br />
-*β-1,4-galactosyltransferase 7 (BGT)
-**[[1tvy]], [[1tw1]], [[4lw3]] - bBGT 7 catalytic domain (mutant) + UDP-galactose<br />
-**[[4irq]], [[4irp]] - bBGT 7 catalytic domain + UDP<br />
-**[[4lw6]] - bBGT 7 catalytic domain + xylobiose<br />
-**[[4m4k]] - bBGT 7 catalytic domain (mutant) + UDP-galactose + xylobiose<br />
-**[[3lw6]] - DmBGT 7 catalytic domain (mutant)<br />
-*α-1,3-galactosyltransferase (AGT)
-**[[1vzu]], [[1vzx]], [[2i7b]] - hAGT catalytic domain (mutant)<br />
-**[[2i7b]] - hAGT catalytic domain (mutant)<br />
-**[[1g8o]], [[1fg5]], [[2jco]] - bAGT catalytic domain<br />
-**[[2jcl]] – bAGT catalytic domain (mutant) <br />
-*''AGT binary complexes''
-**[[1ziz]], [[1zjp]] - hAGT catalytic domain + galactose<br />
-**[[1zj0]] - hAGT catalytic domain + lactose<br />
-**[[1zj1]] - hAGT catalytic domain + N-acetyl lactosamine<br />
-**[[1zj2]], [[1zj3]] - hAGT catalytic domain + trisaccharide<br />
-**[[2a8u]], [[2a8w]] - hAGT catalytic domain + methyl lactoside<br />
-**[[1g93]], [[1gx0]] - bAGT catalytic domain + UDP-galactose<br />
-**[[1k4v]] - bAGT catalytic domain + UDP<br />
-**[[2rj0]] - bAGT catalytic domain + UDP + Mn<br />
-**[[1vzt]], [[2jcj]] - bAGT catalytic domain (mutant) + UDP<br />
-**[[2vfz]] - bAGT catalytic domain (mutant) + UDP-2F-galactose<br />
-**[[2vs4]], [[2vs5]], [[2vxl]], [[2vxm]], [[2vs3]] - bAGT catalytic domain (mutant) + UDP-galactose<br />
-**[[2vs3]] - bAGT catalytic domain  + UDP-galactose<br />
-*''AGT ternary complexes''
-**[[1r7u]], [[1r7x]] - hAGT catalytic domain + inhibitor + fucose<br />
-**[[1r80]] - hAGT catalytic domain + UDP + inhibitor + fucose<br />
-**[[1r82]] - hAGT catalytic domain + UDP-galactose + inhibitor + fucose<br />
-**[[1gwv]] - bAGT catalytic domain + UDP + lactose<br />
-**[[2jck]] - bAGT catalytic domain (mutant) + UDP + Mn<br />
-**[[2wgz]] - bAGT catalytic domain + UDP + nitrophenyl-β-galactoside<br />
-**[[1o7o]] - bAGT catalytic domain (mutant) + UDP + lactose<br />
-**[[1gx4]] - bAGT catalytic domain + UDP + N-acetyl lactosamine<br />
-**[[1gww]] - bAGT catalytic domain + UDP + glucose<br />
-*Fucosylglycoprotein 3-AGT (GTB) or histo-blood group ABO system transferase
-**[[2rit]], [[4kxo]] – hGTB<br />
-**[[2pgv]], [[2pgy]], [[2riz]], [[2rj5]], [[1wsz]], [[2o1f]], [[2o1g]], [[5cql]], [[5cqm]], [[5cqn]], [[5cqo]], [[5cqp]], [[5cmf]], [[5cmg]], [[5cmh]], [[5cmi]], [[5cmj]], [[3ioh]], [[6bjm]], [[6bjl]], [[6bjk]], [[6bjj]], [[6bji]], [[6gwz]], [[6gwy]], [[6gx2]], [[6gx1]], [[6gx0]] – hGTB (mutant) <br />
-**[[2rix]] – hGTB + UDP<br />
-**[[3ioj]], [[2olh]], [[5m7b]], [[5m7c]], [[5m7d]] – hGTB (mutant) + UDP<br />
-**[[4gbp]], [[4frq]], [[4fqw]], [[4fre]], [[4frh]], [[4frl]], [[4frm]], [[4fro]], [[4frp]], [[3sxa]], [[3sxb]] – hGTB + UDP-galactose<br />
-**[[4fra]], [[4frb]], [[4frd]], [[3zgf]], [[3zgg]], [[3v0l]], [[3v0m]], [[3v0n]], [[3v0o]], [[3ioi]] – hGTB (mutant) + UDP-galactose<br />
-**[[5m79]], [[5m7a]] – hGTB (mutant) + UMP<br />
-**[[4y62]], [[4y63]], [[4y64]] - hGTB + amino acid analog<br />
-**[[3u0x]] – hGTB + inhibitor<br />
-**[[3u0y]] – hGTB (mutant) + UDP + inhibitor<br />
-**[[2riy]] – hGTB + H-antigen acceptor<br />
-**[[1zi4]], [[1zi5]] - hGTB + H-antigen<br />
-**[[3i0j]] – hGTB Abo (mutant) + H-antigen<br />
-**[[2rj1]], [[2rj6]] - hGTB (mutant) + UDP + H-antigen disaccharide<br />
-**[[2rj8]] - hGTB  + UDP + H-antigen disaccharide<br />
-**[[5tjk]], [[5tjl]], [[5tjn]], [[5tjo]] - hGTB  + UDP + H-antigen trisaccharide<br />
-**[[5c49]] - hGTB (mutant) + UDP-galactose + H-antigen <br />
-**[[2rj4]] - hGTB (mutant) + UDP + ADA<br />
-**[[5bxc]] - hGTB + UDP + deoxy-acceptor<br />
-**[[5c1g]], [[5c1h]], [[4c2s]] - hGTB (mutant) + UDP + deoxy-acceptor<br />
-**[[2rj9]], [[5c36]], [[5c1l]] - hGTB + UDP-galactose + deoxy-acceptor<br />
-**[[2rj7]], [[5c47]], [[5c48]], [[5c38]], [[5c3a]], [[5c3b]], [[5c3d]], [[3v0p]], [[3v0q]] - hGTB (mutant) + UDP-galactose + deoxy-acceptor<br />
-**[[5c8r]], [[5c4b]] - hGTB + UDP-glucose + deoxy-acceptor<br />
-**[[5c4c]], [[5c4d]], [[5c4e]], [[5c4f]] - hGTB (mutant) + UDP-glucose + deoxy-acceptor<br />
-**[[3sx3]], [[3sx5]], [[3sx7]], [[3sx8]], [[3sxc]], [[3sxd]], [[3sxe]], [[3sxg]], [[1zhj]], [[1zjo]] - hGTB catalytic domain + galactose<br />
-**[[1zi1]] - hGTB catalytic domain + lactose<br />
-**[[1zi3]] - hGTB catalytic domain + acetylactosamine
-}}
 == References ==
 <references/>
 [[Category:Topic Page]]