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Gp41
From Proteopedia
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<StructureSection load='1aik' size='340' side='right' caption='Core structure of acetylated gp41 from the HIV envelope glycoprotein, [[1aik]].' scene=''> | <StructureSection load='1aik' size='340' side='right' caption='Core structure of acetylated gp41 from the HIV envelope glycoprotein, [[1aik]].' scene=''> | ||
== Function == | == Function == | ||
| - | '''Gp41''' is a subunit of the envelope protein of retrovirus<ref>PMID:9630213</ref>. Gp41 is a transmembrane protein and contains several sites which are involved in the infection of the host cells. Gp160 is the cleavable precursor of Gp41 and Gp120. For more details see [[Hiv env proteins]]. | + | '''Gp41''' is a subunit of the envelope protein of retrovirus<ref>PMID:9630213</ref>. Gp41 is a transmembrane protein and contains several sites which are involved in the infection of the host cells. Gp160 is the cleavable precursor of Gp41 and Gp120. For more details see [[Hiv env proteins|HIV-1 viral envelope proteins]]. |
== Relevance == | == Relevance == | ||
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</StructureSection> | </StructureSection> | ||
| - | == 3D Structures of Gp41 == | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *Gp41 from HIV-1; Domains – core 509-661; N-peptide 541-590; transmembrane 670-709; tail 750-854 | ||
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| - | **[[2zfc]], [[3u91]] – Gp41 N-terminal residues 1-49 <br /> | ||
| - | **[[3k9a]] – Gp41 residues 1-108 (mutant)<br /> | ||
| - | **[[1aik]], [[1df4]], [[1df5]], [[1qr8]], [[1qr9]], [[1dlb]], [[1jpx]], [[1szt]], [[3vu5]], [[3vu6]] - Gp41 N-peptide domain <br /> | ||
| - | **[[1env]], [[3cp1]], [[3cyo]], [[1f23]], [[1k33]], [[1k34]], [[1i5x]], [[1i5y]], [[2ot5]], [[5ka6]], [[5ka5]], [[4i2l]] – Gp41 N-peptide domain (mutant)<br /> | ||
| - | **[[2z2t]], [[2zzo]], [[3aha]], [[3vie]], [[2r3c]], [[2r5b]], [[2r5d]], [[3l36]], [[3l37]], [[3vgy]], [[3vh7]], [[3vtp]], [[5h0n]], [[5zpw]] – Gp41 N-peptide domain + fusion inhibitor peptide<br /> | ||
| - | **[[6b3u]], [[6dln]] – Gp41 transmembrane domain - NMR<br /> | ||
| - | **[[5vwl]] – Gp41 tail domain - NMR<br /> | ||
| - | **[[5v8l]], [[5v8m]], [[5uty]], [[5utf]], [[5um8]], [[5jsa]], [[5js9]], [[5i8h]], [[5d9q]], [[5cjx]], [[5c7k]], [[6ck9]], [[6chb]], [[6ch9]], [[6ch8]], [[6ch7]], [[5w6d]], [[4nrx]], [[5fyk]], [[5fyj]], [[4nco]], [[6mdt]], [[6mco]] – Gp41 core + Gp120 + antibody<br /> | ||
| - | **[[6nnj]], [[6nnf]], [[6nm6]] – Gp41 core (mutant) + Gp120 + antibody<br /> | ||
| - | **[[6cdi]], [[6orn]], [[6oo]], [[6orp]], [[6orq]], [[6okp]], [[6nqd]], [[6mn7]], [[6cuf]], [[6cue]] – Gp41 core + Gp120 + antibody – Cryo EM<br /> | ||
| - | **[[6nc3]], [[6nc2]] – Gp41 core (mutant) + Gp120 + antibody – Cryo EM<br /> | ||
| - | **[[5u1f]], [[5thr]] – Gp41 core + Gp120 + antibody + CD4<br /> | ||
| - | **[[5hm1]] – Gp41 core + llama antibody <br /> | ||
| - | **[[3o3x]] – arGp41 - artificial<br /> | ||
| - | **[[4dzu]] – arGp41 + 3-α<br /> | ||
| - | **[[4dzv]] – arGp41 + 4-α/β<br /> | ||
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| - | *Gp41 from Simian Immunodeficiency Virus | ||
| - | **[[2siv]] – Gp41 core<br /> | ||
| - | **[[2ezo]], [[2ezp]], [[2ezq]], [[2ezr]], [[2ezs]], [[1qce]] – Gp41 core - NMR<br /> | ||
| - | **[[1qbz]], [[1jq0]] – Gp41 core (mutant)<br /> | ||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
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