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4atd

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<StructureSection load='4atd' size='340' side='right'caption='[[4atd]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='4atd' size='340' side='right'caption='[[4atd]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4atd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ophioxylon_serpentinum Ophioxylon serpentinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ATD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ATD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4atd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rauvolfia_serpentina Rauvolfia serpentina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ATD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ATD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4a3y|4a3y]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Raucaffricine_beta-glucosidase Raucaffricine beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.125 3.2.1.125] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4atd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4atd OCA], [https://pdbe.org/4atd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4atd RCSB], [https://www.ebi.ac.uk/pdbsum/4atd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4atd ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4atd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4atd OCA], [http://pdbe.org/4atd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4atd RCSB], [http://www.ebi.ac.uk/pdbsum/4atd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4atd ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RG1_RAUSE RG1_RAUSE] Glucosidase specifically involved in alkaloid biosynthesis leading to the accumulation of several alkaloids, including ajmaline, an important plant-derived pharmaceutical used in the treatment of heart disorders.<ref>PMID:10975500</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ophioxylon serpentinum]]
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[[Category: Rauvolfia serpentina]]
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[[Category: Raucaffricine beta-glucosidase]]
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[[Category: Panjikar S]]
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[[Category: Panjikar, S]]
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[[Category: Rajendran C]]
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[[Category: Rajendran, C]]
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[[Category: Ruppert M]]
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[[Category: Ruppert, M]]
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[[Category: Stoeckigt J]]
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[[Category: Stoeckigt, J]]
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[[Category: Wang M]]
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[[Category: Wang, M]]
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[[Category: Xia L]]
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[[Category: Xia, L]]
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[[Category: Alkaloid]]
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[[Category: Hydrolase]]
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Current revision

Crystal structure of native Raucaffricine glucosidase

PDB ID 4atd

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OCA

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