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4tlr

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<StructureSection load='4tlr' size='340' side='right'caption='[[4tlr]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
<StructureSection load='4tlr' size='340' side='right'caption='[[4tlr]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4tlr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hcv Hcv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TLR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TLR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4tlr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_(isolate_1) Hepatitis C virus (isolate 1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TLR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TLR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=33H:3-{(2R,5R)-5-CYCLOHEXYL-2-[(2R)-2-HYDROXYPROPYL]-3-OXOMORPHOLIN-4-YL}-5-(3,3-DIMETHYLBUT-1-YN-1-YL)THIOPHENE-2-CARBOXYLIC+ACID'>33H</scene>, <scene name='pdbligand=79Z:5-CYCLOPROPYL-2-(4-FLUOROPHENYL)-6-[(2-HYDROXYETHYL)(METHYLSULFONYL)AMINO]-N-METHYL-1-BENZOFURAN-3-CARBOXAMIDE'>79Z</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=33H:3-{(2R,5R)-5-CYCLOHEXYL-2-[(2R)-2-HYDROXYPROPYL]-3-OXOMORPHOLIN-4-YL}-5-(3,3-DIMETHYLBUT-1-YN-1-YL)THIOPHENE-2-CARBOXYLIC+ACID'>33H</scene>, <scene name='pdbligand=79Z:5-CYCLOPROPYL-2-(4-FLUOROPHENYL)-6-[(2-HYDROXYETHYL)(METHYLSULFONYL)AMINO]-N-METHYL-1-BENZOFURAN-3-CARBOXAMIDE'>79Z</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tlr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tlr OCA], [http://pdbe.org/4tlr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tlr RCSB], [http://www.ebi.ac.uk/pdbsum/4tlr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tlr ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tlr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tlr OCA], [https://pdbe.org/4tlr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tlr RCSB], [https://www.ebi.ac.uk/pdbsum/4tlr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tlr ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
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*[[RNA polymerase|RNA polymerase]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Hcv]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Chopra R]]
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[[Category: Chopra, R]]
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[[Category: Complex polymerase inhbitor]]
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[[Category: Hydrolase]]
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Current revision

NS5b in complex with lactam-thiophene carboxylic acids

PDB ID 4tlr

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