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2p3z

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<StructureSection load='2p3z' size='340' side='right'caption='[[2p3z]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='2p3z' size='340' side='right'caption='[[2p3z]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2p3z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2P3Z FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2p3z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P3Z FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gsh|2gsh]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yfaW, STM2291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3z OCA], [https://pdbe.org/2p3z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p3z RCSB], [https://www.ebi.ac.uk/pdbsum/2p3z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p3z ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2p3z TOPSAN]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-rhamnonate_dehydratase L-rhamnonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.90 4.2.1.90] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3z OCA], [http://pdbe.org/2p3z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2p3z RCSB], [http://www.ebi.ac.uk/pdbsum/2p3z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2p3z ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/2p3z TOPSAN]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RHMD_SALTY RHMD_SALTY]] Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR). Can also dehydrate L-lyxonate and L-mannonate, although less efficiently, but not 2-keto-4-hydroxyheptane-1,7-dioate.<ref>PMID:18754693</ref>
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[https://www.uniprot.org/uniprot/RHMD_SALTY RHMD_SALTY] Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR). Can also dehydrate L-lyxonate and L-mannonate, although less efficiently, but not 2-keto-4-hydroxyheptane-1,7-dioate.<ref>PMID:18754693</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: L-rhamnonate dehydratase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Salty]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Adams, J M]]
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[[Category: Adams JM]]
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[[Category: Almo, S C]]
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[[Category: Almo SC]]
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[[Category: Burley, S K]]
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[[Category: Burley SK]]
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[[Category: Dickey, M]]
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[[Category: Dickey M]]
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[[Category: Gerlt, J]]
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[[Category: Gerlt J]]
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[[Category: Malashkevich, V N]]
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[[Category: Malashkevich VN]]
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[[Category: Structural genomic]]
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[[Category: Sauder JM]]
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[[Category: Sauder, J M]]
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[[Category: Wasserman SR]]
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[[Category: Wasserman, S R]]
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[[Category: Enolase]]
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[[Category: Lyase]]
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[[Category: Nysgrc]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: PSI, Protein structure initiative]]
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Current revision

Crystal structure of L-Rhamnonate dehydratase from Salmonella typhimurium

PDB ID 2p3z

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